Structural Classification of Proteins
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Root: scop

Classes:

  1. All alpha proteins [46456] (258)
    1. Globin-like [46457] (2)
      core: 6 helices; folded leaf, partly opened
      1. Globin-like [46458] (4) picpic
      2. alpha-helical ferredoxin [46548] (2) picpic
        contains two Fe4-S4 clusters
    2. Long alpha-hairpin [46556] (19)
      2 helices; antiparallel hairpin, left-handed twist
      1. GreA transcript cleavage protein, N-terminal domain [46557] (1) picpic
      2. Ribosomal protein L29 (L29p) [46561] (1) picpic
      3. Chaperone J-domain [46565] (1) picpic
      4. Prefoldin [46579] (1) picpic
      5. HR1 repeat [46585] (1) picpic
      6. tRNA-binding arm [46589] (4) picpic
        formerly a class II aminoacyl-tRNA synthetase N-domain
      7. Eukaryotic DNA topoisomerase I, dispensable insert domain [46596] (1) picpic
      8. C-terminal UvrC-binding domain of UvrB [46600] (1) picpic
      9. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46604] (1) picpic
      10. Fe,Mn superoxide dismutase (SOD), N-terminal domain [46609] (1) picpic
      11. Sporulation inhibitor Sda [100985] (1) picpic
      12. Transcriptional repressor TraM [109631] (1) picpic
        similar structure to L29p (scop_sf 46561); contains extra short helix; forms homodimer: an open bundle
      13. DnaK suppressor protein DksA, alpha-hairpin domain [109635] (1) picpic
      14. ISY1 domain-like [140102] (1) picpic
      15. Calcyclin-binding protein-like [140106] (1) picpic
      16. Endosomal sorting complex assembly domain [140111] (3) picpic
        forms 'fan'-like heterooligomers, in which the domains of different subunit make similar interactions at the tip of the hairpin
      17. SPy1572-like [140121] (1) picpic
        forms homodimer: an open bundle, different from the TRAM dimer
      18. Rabenosyn-5 Rab-binding domain-like [140125] (1) picpic
      19. MxiH-like [140129] (1) picpic
        Type III secretion system needle
    3. Type I dockerin domain [63445] (1)
      tandem repeat of two calcium-binding loop-helix motifs, distinct from the EF-hand
      1. Type I dockerin domain [63446] (1) picpic
    4. LEM/SAP HeH motif [63450] (5)
      helix-extended loop-helix; parallel helices
      1. LEM domain [63451] (1) picpic
      2. SAP domain [68906] (1) picpic
      3. Rho termination factor, N-terminal domain [68912] (1) picpic
      4. Recombination endonuclease VII, C-terminal and dimerization domains [68918] (1) picpic
      5. DNA-binding domain of EIN3-like [116768] (1) picpic
        decorated with additional structures
    5. RPB6/omega subunit-like [63561] (1)
      core: 2 helices and adjacent loops
      1. RPB6/omega subunit-like [63562] (2) picpic
        the bacterial omega and eukaryotic RPB6 subunits both function in polymerase assembly; the common core is involved in conserved interactions with other subunits
    6. KRAB domain (Kruppel-associated box) [109639] (1)
      2 helices: one short, one long; aromatic-rich iterface
      1. KRAB domain (Kruppel-associated box) [109640] (1) picpic
    7. Cytochrome c [46625] (1)
      core: 3 helices; folded leaf, opened
      1. Cytochrome c [46626] (8) picpic
        covalently-bound heme completes the core
    8. DNA/RNA-binding 3-helical bundle [46688] (14)
      core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
      1. Homeodomain-like [46689] (17) picpic
        consists only of helices
      2. Methylated DNA-protein cysteine methyltransferase, C-terminal domain [46767] (1) picpic
      3. ARID-like [46774] (1) picpic
        contains extra helices at both N- and C-termini
      4. "Winged helix" DNA-binding domain [46785] (68) picpic
        contains a small beta-sheet (wing)
      5. C-terminal effector domain of the bipartite response regulators [46894] (3) picpic
        binds to DNA and RNA polymerase; the N-terminal, receiver domain belongs to the CheY family
      6. TrpR-like [48295] (2) picpic
        contains an extra shared helix after the HTH motif
      7. Ribosomal protein L11, C-terminal domain [46906] (1) picpic
      8. Ribosomal protein S18 [46911] (1) picpic
      9. Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 [46915] (1) picpic
      10. N-terminal Zn binding domain of HIV integrase [46919] (1) picpic
      11. RNA polymerase subunit RPB10 [46924] (1) picpic
      12. Sigma3 and sigma4 domains of RNA polymerase sigma factors [88659] (3) picpic
      13. KorB DNA-binding domain-like [109709] (1) picpic
        contains HTH motif in the common core; also contains extra N-terminal helix and C-terminal subdomain of 4 helices (left-handed superhelix)
      14. Rps17e-like [116820] (1) picpic
    9. Another 3-helical bundle [81602] (5)
      topologically similar to the DNA/RNA-binding bundles; distinct packing
      1. FF domain [81698] (1) picpic
      2. Protein serine/threonine phosphatase 2C, C-terminal domain [81601] (1) picpic
      3. B-form DNA mimic Ocr [101059] (1) picpic
      4. DEK C-terminal domain [109715] (1) picpic
      5. IscX-like [140319] (1) picpic
    10. RuvA C-terminal domain-like [46928] (9)
      3 helices; bundle, right-handed twist
      1. DNA helicase RuvA subunit, C-terminal domain [46929] (1) picpic
        possibly related to UBA-like domains
      2. UBA-like [46934] (4) picpic
      3. post-HMGL domain-like [89000] (2) picpic
      4. CRAL/TRIO N-terminal domain [46938] (1) picpic
      5. Elongation factor TFIIS domain 2 [46942] (1) picpic
      6. Double-stranded DNA-binding domain [46950] (1) picpic
      7. Hypothetical protein AF0491, middle domain [109728] (1) picpic
      8. HBS1-like domain [109732] (1) picpic
        possibly related to UBA-like domains
      9. FGAM synthase PurL, linker domain [109736] (1) picpic
    11. S13-like H2TH domain [81297] (1)
      core: 3-4 helices
      1. S13-like H2TH domain [46946] (3) picpic
        contains a helix-two turns-helix (H2TH) motif
    12. Putative DNA-binding domain [46954] (1)
      core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different
      1. Putative DNA-binding domain [46955] (7) picpic
    13. Spectrin repeat-like [46965] (15)
      3 helices; bundle, closed, left-handed twist; up-and-down
      1. Spectrin repeat [46966] (1) picpic
      2. Enzyme IIa from lactose specific PTS, IIa-lac [46973] (1) picpic
      3. Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain [46977] (1) picpic
      4. Smac/diablo [46984] (1) picpic
      5. BAG domain [63491] (1) picpic
      6. GAT-like domain [89009] (2) picpic
      7. Tubulin chaperone cofactor A [46988] (1) picpic
      8. Ribosomal protein S20 [46992] (1) picpic
      9. Glycogen synthesis protein GlgS [109747] (1) picpic
      10. Alpha-hemoglobin stabilizing protein AHSP [109751] (1) picpic
        the bundle twist angle is close to zero (small positive value); similar to the RRF alpha-helical bundle, scop_sf 55194
      11. PhoU-like [109755] (1) picpic
        duplication: consists of two sequence each repeats adopting this fold
      12. XseB-like [116842] (1) picpic
        helix-swapped homodimer
      13. MIT domain [116846] (1) picpic
      14. PPK N-terminal domain-like [140356] (1) picpic
      15. MIT domain-like [140361] (1) picpic
    14. immunoglobulin/albumin-binding domain-like [46996] (10)
      3 helices; bundle, closed, left-handed twist; up-and-down; mirror topology to the spectrin-like fold
      1. Bacterial immunoglobulin/albumin-binding domains [46997] (2) picpic
      2. Plasmid maintenance system epsilon/zeta, antidote epsilon subunit [81710] (1) picpic
      3. Families 57/38 glycoside transferase middle domain [88688] (3) picpic
      4. Phosphoprotein XD domain [101089] (1) picpic
      5. Staphylocoagulase [101094] (1) picpic
        duplication: consists of two domains of this fold
      6. Heat shock protein 70kD (HSP70), C-terminal subdomain [100934] (1) picpic
      7. Typo IV secretion system protein TraC [101082] (1) picpic
      8. Avirulence protein AvrPto [116854] (1) picpic
      9. Coronavirus NSP7-like [140367] (1) picpic
      10. Vng1086c-like [140371] (1) picpic
        homotetramer; comprises two dimers similar to the antidote epsilon subunit dimer
    15. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47004] (1)
      3 helices; bundle, closed, right-handed twist; up-and-down
      1. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47005] (1) picpic
    16. ChaB-like [140375] (1)
      3 helices, the first one is shorter than the other two; bundle, capped by a small, C-terminal beta-hairpin
      1. ChaB-like [140376] (1) picpic
    17. Protozoan pheromone-like [47013] (2)
      3 helices; bundle, closed, left-handed twist, up-and-down
      1. Protozoan pheromone proteins [47014] (1) picpic
      2. Hypothetical membrane protein Ta0354, soluble domain [116858] (1) picpic
    18. Acyl-CoA binding protein-like [47026] (2)
      core: 3 helices; bundle, closed, left-handed twist; up-and-down
      1. Acyl-CoA binding protein [47027] (1) picpic
      2. Second domain of FERM [47031] (1) picpic
    19. Kix domain of CBP (creb binding protein) [47039] (1)
      3 helices; bundle, partly opened
      1. Kix domain of CBP (creb binding protein) [47040] (1) picpic
    20. RAP domain-like [47044] (1)
      3 helices, the first one is shorter than the other two; bundle, partly opened
      1. RAP domain-like [47045] (1) picpic
    21. VHP, Villin headpiece domain [47049] (1)
      3 short helices; irregular array
      1. VHP, Villin headpiece domain [47050] (1) picpic
    22. BSD domain-like [140382] (1)
      core: 3 helices; triangular array; the extra N-terminal and C-terminal helices form a coiled coil structure
      1. BSD domain-like [140383] (1) picpic
    23. TAF(II)230 TBP-binding fragment [47054] (1)
      3 short helices; irregular array
      1. TAF(II)230 TBP-binding fragment [47055] (1) picpic
    24. S15/NS1 RNA-binding domain [47059] (1)
      3 helices; irregular array
      1. S15/NS1 RNA-binding domain [47060] (3) picpic
    25. Frizzled cysteine-rich domain [63500] (1)
      Core: 3 helices; irregular array; disulfide-rich
      1. Frizzled cysteine-rich domain [63501] (1) picpic
    26. T4 endonuclease V [47076] (1)
      3 helices; irregular array
      1. T4 endonuclease V [47077] (1) picpic
    27. Fertilization protein [47081] (1)
      core: 3 helices; bundle, closed, right-handed twist; up-and-down
      1. Fertilization protein [47082] (1) picpic
    28. PGBD-like [47089] (1)
      core: 3 helices; bundle, closed, left-handed twist; parallel
      1. PGBD-like [47090] (2) picpic
    29. HMG-box [47094] (1)
      3 helices; irregular array
      1. HMG-box [47095] (1) picpic
    30. Histone-fold [47112] (1)
      core: 3 helices; long middle helix is flanked at each end with shorter ones
      1. Histone-fold [47113] (4) picpic
    31. Open three-helical up-and-down bundle [47143] (6)
      core: 3 helices; bundle, open
      1. HSC20 (HSCB), C-terminal oligomerisation domain [47144] (1) picpic
      2. Diol dehydratase, gamma subunit [47148] (1) picpic
        contains irregular N-terminal subdomain
      3. Methane monooxygenase hydrolase, gamma subunit [47152] (1) picpic
        duplication: consists of two domains of this fold
      4. Mitochondrial import receptor subunit Tom20 [47157] (1) picpic
      5. Hemolysin expression modulating protein HHA [68989] (1) picpic
      6. EF2458-like [140404] (1) picpic
        N-terminal helix swapped dimer; interrupted antiparallel coiled coil
    32. beta-catenin-interacting protein ICAT [81729] (1)
      core: 3 helices; irregular array
      1. beta-catenin-interacting protein ICAT [81730] (1) picpic
    33. DNA polymerase III theta subunit-like [116730] (1)
      3 helices; irregular array
      1. DNA polymerase III theta subunit-like [46575] (1) picpic
    34. Four-helical up-and-down bundle [47161] (27)
      core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
      1. Apolipoprotein [47162] (1) picpic
      2. Aspartate receptor, ligand-binding domain [47170] (1) picpic
      3. Cytochromes [47175] (2) picpic
        Heme-containing proteins
      4. Hemerythrin [47188] (1) picpic
      5. TMV-like viral coat proteins [47195] (1) picpic
      6. FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1) picpic
      7. Proteasome activator reg(alpha) [47216] (1) picpic
      8. alpha-catenin/vinculin-like [47220] (2) picpic
      9. FAT domain of focal adhesion kinase [68993] (1) picpic
      10. Oxygen-evolving enhancer protein 3, [101112] (1) picpic
      11. Histidine-containing phosphotransfer domain, HPT domain [47226] (5) picpic
        contains additional, fifth helix at the N-terminus
      12. Bacterial GAP domain [47233] (1) picpic
        contains extra helices in the loops at one end of the bundle
      13. Outer surface protein C (OspC) [63515] (1) picpic
      14. Flagellar export chaperone FliS [101116] (1) picpic
        can form closed, open and helix-swapped bundles
      15. Domain of the SRP/SRP receptor G-proteins [47364] (1) picpic
      16. FAD-dependent thiol oxidase [69000] (1) picpic
      17. Group V grass pollen allergen [81736] (1) picpic
      18. Nucleotidyltransferase substrate binding subunit/domain [81593] (4) picpic
      19. RecG, N-terminal domain [69008] (1) picpic
      20. Colicin D immunity protein [101125] (1) picpic
      21. Nickel-containing superoxide dismutase, NiSOD [109770] (1) picpic
      22. Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain [109775] (1) picpic
        contains extra alpha+beta subdomain formed by the N- and C-termini.
      23. Domain from hypothetical 2610208m17rik protein [109779] (1) picpic
      24. TrmE connector domain [116878] (1) picpic
      25. YppE-like [140415] (1) picpic
        flattened bundle at one end with helices 2 and coming in contact and separating helices 1 and 3
      26. MW0975(SA0943)-like [140423] (1) picpic
        open bundle; there is a long groove between helices 1 and 4
      27. VPS28 C-terminal domain-like [140427] (1) picpic
    35. PTS-regulatory domain, PRD [63519] (1)
      core: 4 helices; bundle, closed, right-handed twist; 1 crossover connection
      1. PTS-regulatory domain, PRD [63520] (1) picpic
        duplication: consists of two domains of this fold
    36. Ferritin-like [47239] (4)
      core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
      1. Ferritin-like [47240] (5) picpic
        contains bimetal-ion centre in the middle of the bundle
      2. Cobalamin adenosyltransferase-like [89028] (2) picpic
        crossover loop goes across a different side of the 4-helical bundle; no internal metal-binding site
      3. EsxAB dimer-like [140453] (1) picpic
        (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals
      4. PE/PPE dimer-like [140459] (2) picpic
        (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals inside the bundle
    37. 4-helical cytokines [47265] (1)
      core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
      1. 4-helical cytokines [47266] (3) picpic
        there are two different topoisomers of this fold with different entanglements of the two crossover connections
    38. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1)
      core: 4 helices; bundle; one loop crosses over one side of the bundle
      1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323] (1) picpic
    39. Acyl carrier protein-like [47335] (3)
      4 helices, bundle; helix 3 is shorter than others; up-and-down
      1. ACP-like [47336] (3) picpic
      2. Colicin E immunity proteins [47345] (1) picpic
      3. Retrovirus capsid dimerization domain-like [47353] (2) picpic
    40. Bromodomain-like [47363] (10)
      4 helices; bundle; minor mirror variant of up-and-down topology
      1. Bromodomain [47370] (1) picpic
      2. alpha-ketoacid dehydrogenase kinase, N-terminal domain [69012] (1) picpic
      3. Acyl-CoA dehydrogenase C-terminal domain-like [47203] (2) picpic
        multidomain flavoprotein; N-terminal domain is all-alpha; the middle domain is open (5,8) barrel
      4. Plant invertase/pectin methylesterase inhibitor [101148] (1) picpic
        contains a short alpha-hairpin at the N-terminal extension
      5. Mob1/phocein [101152] (1) picpic
        common fold is elaborated with additional short helices; contains a zinc-binding site
      6. Bacteriocin immunity protein-like [109797] (2) picpic
      7. LemA-like [140478] (1) picpic
        helices 2 and 3 are shorther than helices 1 and 4
      8. MAST3 pre-PK domain-like [140482] (1) picpic
        this domain precedes the Protein Kinase domain in Microtubule-associated serine/threonine-protein kinase 3 (MAST3)
      9. PA2201 N-terminal domain-like [140486] (1) picpic
      10. Nqo1C-terminal domain-like [140490] (1) picpic
        contains extra C-terminal helix that caps the bundle at one end and Fe4-S4 cluster at the other end
    41. ROP-like [47379] (8)
      4 helices; dimer of identical alpha-hairpin subunits; bundle, closed, left-handed twist
      1. ROP protein [47380] (1) picpic
      2. Homodimeric domain of signal transducing histidine kinase [47384] (1) picpic
      3. Nonstructural protein ns2, Nep, M1-binding domain [101156] (1) picpic
      4. Dimerisation domain of CENP-B [101160] (1) picpic
      5. Hypothetical protein D-63 [109801] (1) picpic
      6. HP1531-like [140496] (1) picpic
        contains short extra helix in the loop between the two bundle-forming helices
      7. BAS1536-like [140500] (1) picpic
      8. FHV B2 protein-like [140506] (1) picpic
    42. Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit [47390] (1)
      4 helices; bundle, closed, right-handed twist
      1. Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit [47391] (1) picpic
        dimer of identical alpha-hairpin motifs
    43. Soluble domain of poliovirus core protein 3a [89042] (1)
      4 helices; bundle, closed, right-handed twist
      1. Soluble domain of poliovirus core protein 3a [89043] (1) picpic
        dimer of identical alpha-hairpin motifs
    44. Transcription factor IIA (TFIIA), alpha-helical domain [47395] (1)
      4 helices; bundle, closed, right-handed twist
      1. Transcription factor IIA (TFIIA), alpha-helical domain [47396] (1) picpic
        dimer of non-identical alpha-hairpins
    45. Ectatomin subunits [47400] (1)
      4 helices; bundle, closed, left-handed twist
      1. Ectatomin subunits [47401] (1) picpic
        disulfide-linked heterodimer of similar alpha-hairpin subunits
    46. Dimerisation interlock [47405] (4)
      4 helices; bundle, closed, right-handed twist
      1. SinR repressor dimerisation domain-like [47406] (1) picpic
        intertwined heterodimer of two homologous chains
      2. Dimerization cofactor of HNF-1 alpha [100957] (1) picpic
      3. Docking domain A of the erythromycin polyketide synthase (DEBS) [101166] (1) picpic
      4. Phenylalanine zipper [109805] (1) picpic
        interlocking dimer with longer helices and aromatic-rich core
    47. lambda repressor-like DNA-binding domains [47412] (1)
      core: 4 helices; folded leaf, closed
      1. lambda repressor-like DNA-binding domains [47413] (13) picpic
    48. Signal peptide-binding domain [47445] (1)
      4 helices; orthogonal array
      1. Signal peptide-binding domain [47446] (1) picpic
    49. A DNA-binding domain in eukaryotic transcription factors [47453] (1)
      4 helices; the long C-terminal helix protrudes from the domain and binds to DNA
      1. A DNA-binding domain in eukaryotic transcription factors [47454] (1) picpic
    50. HLH-like [47458] (2)
      4-helices; bundle, closed, left-handed twist; 2 crossover connections
      1. HLH, helix-loop-helix DNA-binding domain [47459] (1) picpic
        dimer of two identical helix-loop-helix subunits
      2. Docking domain B of the erythromycin polyketide synthase (DEBS) [101173] (1) picpic
    51. EF Hand-like [47472] (4)
      core: 4 helices; array of 2 hairpins, opened
      1. EF-hand [47473] (11) picpic
        Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
      2. Insect pheromone/odorant-binding proteins [47565] (1) picpic
        the N-terminal extension, containing a few short helices, forms a flexible lid for the binding cavity
      3. Hypothetical protein MTH865 [69025] (1) picpic
      4. Cloroperoxidase [47571] (1) picpic
        duplication: consists of 2 similar domains composed of 2 EF hand-like motifs each
    52. CH domain-like [47575] (3)
      core: 4 helices: bundle
      1. Calponin-homology domain, CH-domain [47576] (1) picpic
      2. X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain [81761] (1) picpic
      3. Hook domain [116907] (1) picpic
    53. Domain of poly(ADP-ribose) polymerase [47586] (1)
      core: 4 helices: bundle; unusual topology
      1. Domain of poly(ADP-ribose) polymerase [47587] (1) picpic
        duplication: consists of 2 helix-loop-helix structural repeats
    54. SWIB/MDM2 domain [47591] (1)
      core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
      duplication: consists of two structural repeats
      1. SWIB/MDM2 domain [47592] (1) picpic
        binds to the transactivation domain of human p53
    55. Pre-protein crosslinking domain of SecA [81766] (1)
      core: 4 helices: bundle; flanked by two short beta-hairpins
      duplication: consists of two structural repeats
      1. Pre-protein crosslinking domain of SecA [81767] (1) picpic
    56. Ribbon-helix-helix [47597] (1)
      core: 4 helices; array of 2 hairpins, opened
      1. Ribbon-helix-helix [47598] (8) picpic
        formerly Met repressor-like; dimeric proteins; the N-termini form a small beta-sheet ribbon
    57. Glutathione S-transferase (GST), C-terminal domain [47615] (1)
      core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix
      1. Glutathione S-transferase (GST), C-terminal domain [47616] (1) picpic
        this domains follows the thioredoxin-like N-terminal domain
    58. Methionine synthase domain-like [47643] (3)
      4 helices; bundle, left-handed twist; right-handed superhelix
      1. Methionine synthase domain [47644] (1) picpic
      2. Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain [47648] (1) picpic
      3. TM0693-like [140560] (1) picpic
        helix-swapped dimer; in which the two last helices of this fold form a single coiled-coil helix
    59. KaiA/RbsU domain [101214] (1)
      4 helices; bundle, right-handed twist; right-handed superhelix
      1. KaiA/RbsU domain [101215] (2) picpic
    60. STAT-like [47654] (6)
      4 long helices; bundle, left-handed twist (coiled coil); right-handed superhelix
      1. STAT [47655] (1) picpic
      2. t-snare proteins [47661] (1) picpic
      3. Cag-Z [109839] (1) picpic
        four-helical bundle without significant twist
      4. CAPPD, an extracellular domain of amyloid beta A4 protein [109843] (1) picpic
        the first three helices are longer than the fourth one and, taken separately, adopt a Spectrin repeat-like fold (scop_cf 46965)
      5. FlgN-like [140566] (1) picpic
        the last helix is shorter than the three others; a short extra helix between helices 2 an 3 fills the gap in the bundle
      6. MukF C-terminal domain-like [140570] (1) picpic
    61. N-cbl like [47667] (4)
      4 helices; bundle, left-handed twist; left-handed superhelix
      1. N-terminal domain of cbl (N-cbl) [47668] (1) picpic
      2. Transferrin receptor-like dimerisation domain [47672] (1) picpic
      3. Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 [47676] (1) picpic
      4. HIV integrase-binding domain [140576] (1) picpic
    62. Replisome organizer (g39p helicase loader/inhibitor protein) [89063] (1)
      4 helices; bundle, right-handed twist; left-handed superhelix
      1. Replisome organizer (g39p helicase loader/inhibitor protein) [89064] (1) picpic
    63. Hypothetical protein YqbG [116914] (1)
      core: 4 helices; bundle, right-handed twist; left-handed superhelix
      1. Hypothetical protein YqbG [116915] (1) picpic
    64. C-terminal domain of B transposition protein [47680] (1)
      4 helices; irregular array
      1. C-terminal domain of B transposition protein [47681] (1) picpic
    65. HAND domain of the nucleosome remodeling ATPase ISWI [101223] (1)
      4 helices; irregular array
      1. HAND domain of the nucleosome remodeling ATPase ISWI [101224] (1) picpic
    66. N-terminal, cytoplasmic domain of anti-sigmaE factor RseA [89068] (1)
      4 helices; irregular array
      1. N-terminal, cytoplasmic domain of anti-sigmaE factor RseA [89069] (1) picpic
    67. Anaphylotoxins (complement system) [47685] (1)
      4 helices; irregular array, disulfide-linked
      1. Anaphylotoxins (complement system) [47686] (1) picpic
    68. Cytochrome c oxidase subunit h [47693] (1)
      4 helices; irregular array, disulfide-linked
      1. Cytochrome c oxidase subunit h [47694] (1) picpic
    69. Crustacean CHH/MIH/GIH neurohormone [81777] (1)
      4 helices; irregular array, disulfide-linked
      1. Crustacean CHH/MIH/GIH neurohormone [81778] (1) picpic
    70. C-terminal domain of DFF45/ICAD (DFF-C domain) [81782] (1)
      4 helices; folded leaf; right-handed superhelix
      1. C-terminal domain of DFF45/ICAD (DFF-C domain) [81783] (1) picpic
    71. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47698] (1)
      4 helices; folded leaf; right-handed superhelix
      1. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47699] (3) picpic
        can be classified as disulfide-rich
    72. p53 tetramerization domain [47718] (1)
      core: 4 helices; bundle
      1. p53 tetramerization domain [47719] (1) picpic
        homotetramer
    73. Bcr-Abl oncoprotein oligomerization domain [69035] (1)
      core: 4 long helices; bundle
      1. Bcr-Abl oncoprotein oligomerization domain [69036] (1) picpic
        homotetramer
    74. Domain of early E2A DNA-binding protein, ADDBP [47723] (1)
      4 helices; bundle, partly opened
      1. Domain of early E2A DNA-binding protein, ADDBP [47724] (1) picpic
        this domain is the first in the fragment of known structure
    75. IHF-like DNA-binding proteins [47728] (1)
      core: 4 helices; bundle, partly opened, capped with a beta-sheet
      1. IHF-like DNA-binding proteins [47729] (2) picpic
        dimer of identical subunits
    76. TraM-like [140580] (1)
      multihelical oligomeric protein; structure of whole subunit is not known; the N-terminal part is implicated in DNA binding, the middle region forms tetrameric parallel coiled coil, surrounded by the C-terminal helices
      1. TraM-like [140581] (1) picpic