Class: All alpha proteins

Lineage:

1. Root: scop
2. Class: All alpha proteins [46456]

Folds:

1. Globin-like [46457] (2)
   core: 6 helices; folded leaf, partly opened
   1. Globin-like [46458] (4)
   2. alpha-helical ferredoxin [46548] (2)
      contains two Fe4-S4 clusters
2. Long alpha-hairpin [46556] (19)
   2 helices; antiparallel hairpin, left-handed twist
   1. GreA transcript cleavage protein, N-terminal domain [46557] (1)
   2. Ribosomal protein L29 (L29p) [46561] (1)
   3. Chaperone J-domain [46565] (1)
   4. Prefoldin [46579] (1)
   5. HR1 repeat [46585] (1)
   6. tRNA-binding arm [46589] (4)
      formerly a class II aminoacyl-tRNA synthetase N-domain
   7. Eukaryotic DNA topoisomerase I, dispensable insert domain [46596] (1)
   8. C-terminal UvrC-binding domain of UvrB [46600] (1)
   9. Epsilon subunit of F1F0-ATP synthase C-terminal domain [46604] (1)
   10. Fe,Mn superoxide dismutase (SOD), N-terminal domain [46609] (1)
   11. Sporulation inhibitor Sda [100985] (1)
   12. Transcriptional repressor TraM [109631] (1)
       similar structure to L29p (scop_sf 46561); contains extra short helix; forms homodimer: an open bundle
   13. DnaK suppressor protein DksA, alpha-hairpin domain [109635] (1)
   14. ISY1 domain-like [140102] (1)
   15. Calcyclin-binding protein-like [140106] (1)
   16. Endosomal sorting complex assembly domain [140111] (3)
       forms 'fan'-like heterooligomers, in which the domains of different subunit make similar interactions at the tip of the hairpin
   17. SPy1572-like [140121] (1)
       forms homodimer: an open bundle, different from the TRAM dimer
   18. Rabenosyn-5 Rab-binding domain-like [140125] (1)
   19. MxiH-like [140129] (1)
       Type III secretion system needle
3. Type I dockerin domain [63445] (1)
   tandem repeat of two calcium-binding loop-helix motifs, distinct from the EF-hand
   1. Type I dockerin domain [63446] (1)
4. LEM/SAP HeH motif [63450] (5)
   helix-extended loop-helix; parallel helices
   1. LEM domain [63451] (1)
   2. SAP domain [68906] (1)
   3. Rho termination factor, N-terminal domain [68912] (1)
   4. Recombination endonuclease VII, C-terminal and dimerization domains [68918] (1)
   5. DNA-binding domain of EIN3-like [116768] (1)
      decorated with additional structures
5. RPB6/omega subunit-like [63561] (1)
   core: 2 helices and adjacent loops
   1. RPB6/omega subunit-like [63562] (2)
      the bacterial omega and eukaryotic RPB6 subunits both function in polymerase assembly; the common core is involved in conserved interactions with other subunits
6. KRAB domain (Kruppel-associated box) [109639] (1)
   2 helices: one short, one long; aromatic-rich iterface
   1. KRAB domain (Kruppel-associated box) [109640] (1)
7. Cytochrome c [46625] (1)
   core: 3 helices; folded leaf, opened
   1. Cytochrome c [46626] (8)
      covalently-bound heme completes the core
8. DNA/RNA-binding 3-helical bundle [46688] (14)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
   1. Homeodomain-like [46689] (17)
      consists only of helices
   2. Methylated DNA-protein cysteine methyltransferase, C-terminal domain [46767] (1)
   3. ARID-like [46774] (1)
      contains extra helices at both N- and C-termini
   4. "Winged helix" DNA-binding domain [46785] (68)
      contains a small beta-sheet (wing)
   5. C-terminal effector domain of the bipartite response regulators [46894] (3)
      binds to DNA and RNA polymerase; the N-terminal, receiver domain belongs to the CheY family
   6. TrpR-like [48295] (2)
      contains an extra shared helix after the HTH motif
   7. Ribosomal protein L11, C-terminal domain [46906] (1)
   8. Ribosomal protein S18 [46911] (1)
   9. Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 [46915] (1)
   10. N-terminal Zn binding domain of HIV integrase [46919] (1)
   11. RNA polymerase subunit RPB10 [46924] (1)
   12. Sigma3 and sigma4 domains of RNA polymerase sigma factors [88659] (3)
   13. KorB DNA-binding domain-like [109709] (1)
       contains HTH motif in the common core; also contains extra N-terminal helix and C-terminal subdomain of 4 helices (left-handed superhelix)
   14. Rps17e-like [116820] (1)
9. Another 3-helical bundle [81602] (5)
   topologically similar to the DNA/RNA-binding bundles; distinct packing
   1. FF domain [81698] (1)
   2. Protein serine/threonine phosphatase 2C, C-terminal domain [81601] (1)
   3. B-form DNA mimic Ocr [101059] (1)
   4. DEK C-terminal domain [109715] (1)
   5. IscX-like [140319] (1)
10. RuvA C-terminal domain-like [46928] (9)
    3 helices; bundle, right-handed twist
    1. DNA helicase RuvA subunit, C-terminal domain [46929] (1)
       possibly related to UBA-like domains
    2. UBA-like [46934] (4)
    3. post-HMGL domain-like [89000] (2)
    4. CRAL/TRIO N-terminal domain [46938] (1)
    5. Elongation factor TFIIS domain 2 [46942] (1)
    6. Double-stranded DNA-binding domain [46950] (1)
    7. Hypothetical protein AF0491, middle domain [109728] (1)
    8. HBS1-like domain [109732] (1)
       possibly related to UBA-like domains
    9. FGAM synthase PurL, linker domain [109736] (1)
11. S13-like H2TH domain [81297] (1)
    core: 3-4 helices
    1. S13-like H2TH domain [46946] (3)
       contains a helix-two turns-helix (H2TH) motif
12. Putative DNA-binding domain [46954] (1)
    core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different
    1. Putative DNA-binding domain [46955] (7)
13. Spectrin repeat-like [46965] (15)
    3 helices; bundle, closed, left-handed twist; up-and-down
    1. Spectrin repeat [46966] (1)
    2. Enzyme IIa from lactose specific PTS, IIa-lac [46973] (1)
    3. Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain [46977] (1)
    4. Smac/diablo [46984] (1)
    5. BAG domain [63491] (1)
    6. GAT-like domain [89009] (2)
    7. Tubulin chaperone cofactor A [46988] (1)
    8. Ribosomal protein S20 [46992] (1)
    9. Glycogen synthesis protein GlgS [109747] (1)
    10. Alpha-hemoglobin stabilizing protein AHSP [109751] (1)
        the bundle twist angle is close to zero (small positive value); similar to the RRF alpha-helical bundle, scop_sf 55194
    11. PhoU-like [109755] (1)
        duplication: consists of two sequence each repeats adopting this fold
    12. XseB-like [116842] (1)
        helix-swapped homodimer
    13. MIT domain [116846] (1)
    14. PPK N-terminal domain-like [140356] (1)
    15. MIT domain-like [140361] (1)
14. immunoglobulin/albumin-binding domain-like [46996] (10)
    3 helices; bundle, closed, left-handed twist; up-and-down; mirror topology to the spectrin-like fold
    1. Bacterial immunoglobulin/albumin-binding domains [46997] (2)
    2. Plasmid maintenance system epsilon/zeta, antidote epsilon subunit [81710] (1)
    3. Families 57/38 glycoside transferase middle domain [88688] (3)
    4. Phosphoprotein XD domain [101089] (1)
    5. Staphylocoagulase [101094] (1)
       duplication: consists of two domains of this fold
    6. Heat shock protein 70kD (HSP70), C-terminal subdomain [100934] (1)
    7. Typo IV secretion system protein TraC [101082] (1)
    8. Avirulence protein AvrPto [116854] (1)
    9. Coronavirus NSP7-like [140367] (1)
    10. Vng1086c-like [140371] (1)
        homotetramer; comprises two dimers similar to the antidote epsilon subunit dimer
15. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47004] (1)
    3 helices; bundle, closed, right-handed twist; up-and-down
    1. Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex [47005] (1)
16. ChaB-like [140375] (1)
    3 helices, the first one is shorter than the other two; bundle, capped by a small, C-terminal beta-hairpin
    1. ChaB-like [140376] (1)
17. Protozoan pheromone-like [47013] (2)
    3 helices; bundle, closed, left-handed twist, up-and-down
    1. Protozoan pheromone proteins [47014] (1)
    2. Hypothetical membrane protein Ta0354, soluble domain [116858] (1)
18. Acyl-CoA binding protein-like [47026] (2)
    core: 3 helices; bundle, closed, left-handed twist; up-and-down
    1. Acyl-CoA binding protein [47027] (1)
    2. Second domain of FERM [47031] (1)
19. Kix domain of CBP (creb binding protein) [47039] (1)
    3 helices; bundle, partly opened
    1. Kix domain of CBP (creb binding protein) [47040] (1)
20. RAP domain-like [47044] (1)
    3 helices, the first one is shorter than the other two; bundle, partly opened
    1. RAP domain-like [47045] (1)
21. VHP, Villin headpiece domain [47049] (1)
    3 short helices; irregular array
    1. VHP, Villin headpiece domain [47050] (1)
22. BSD domain-like [140382] (1)
    core: 3 helices; triangular array; the extra N-terminal and C-terminal helices form a coiled coil structure
    1. BSD domain-like [140383] (1)
23. TAF(II)230 TBP-binding fragment [47054] (1)
    3 short helices; irregular array
    1. TAF(II)230 TBP-binding fragment [47055] (1)
24. S15/NS1 RNA-binding domain [47059] (1)
    3 helices; irregular array
    1. S15/NS1 RNA-binding domain [47060] (3)
25. Frizzled cysteine-rich domain [63500] (1)
    Core: 3 helices; irregular array; disulfide-rich
    1. Frizzled cysteine-rich domain [63501] (1)
26. T4 endonuclease V [47076] (1)
    3 helices; irregular array
    1. T4 endonuclease V [47077] (1)
27. Fertilization protein [47081] (1)
    core: 3 helices; bundle, closed, right-handed twist; up-and-down
    1. Fertilization protein [47082] (1)
28. PGBD-like [47089] (1)
    core: 3 helices; bundle, closed, left-handed twist; parallel
    1. PGBD-like [47090] (2)
29. HMG-box [47094] (1)
    3 helices; irregular array
    1. HMG-box [47095] (1)
30. Histone-fold [47112] (1)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
    1. Histone-fold [47113] (4)
31. Open three-helical up-and-down bundle [47143] (6)
    core: 3 helices; bundle, open
    1. HSC20 (HSCB), C-terminal oligomerisation domain [47144] (1)
    2. Diol dehydratase, gamma subunit [47148] (1)
       contains irregular N-terminal subdomain
    3. Methane monooxygenase hydrolase, gamma subunit [47152] (1)
       duplication: consists of two domains of this fold
    4. Mitochondrial import receptor subunit Tom20 [47157] (1)
    5. Hemolysin expression modulating protein HHA [68989] (1)
    6. EF2458-like [140404] (1)
       N-terminal helix swapped dimer; interrupted antiparallel coiled coil
32. beta-catenin-interacting protein ICAT [81729] (1)
    core: 3 helices; irregular array
    1. beta-catenin-interacting protein ICAT [81730] (1)
33. DNA polymerase III theta subunit-like [116730] (1)
    3 helices; irregular array
    1. DNA polymerase III theta subunit-like [46575] (1)
34. Four-helical up-and-down bundle [47161] (27)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
    1. Apolipoprotein [47162] (1)
    2. Aspartate receptor, ligand-binding domain [47170] (1)
    3. Cytochromes [47175] (2)
       Heme-containing proteins
    4. Hemerythrin [47188] (1)
    5. TMV-like viral coat proteins [47195] (1)
    6. FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1)
    7. Proteasome activator reg(alpha) [47216] (1)
    8. alpha-catenin/vinculin-like [47220] (2)
    9. FAT domain of focal adhesion kinase [68993] (1)
    10. Oxygen-evolving enhancer protein 3, [101112] (1)
    11. Histidine-containing phosphotransfer domain, HPT domain [47226] (5)
        contains additional, fifth helix at the N-terminus
    12. Bacterial GAP domain [47233] (1)
        contains extra helices in the loops at one end of the bundle
    13. Outer surface protein C (OspC) [63515] (1)
    14. Flagellar export chaperone FliS [101116] (1)
        can form closed, open and helix-swapped bundles
    15. Domain of the SRP/SRP receptor G-proteins [47364] (1)
    16. FAD-dependent thiol oxidase [69000] (1)
    17. Group V grass pollen allergen [81736] (1)
    18. Nucleotidyltransferase substrate binding subunit/domain [81593] (4)
    19. RecG, N-terminal domain [69008] (1)
    20. Colicin D immunity protein [101125] (1)
    21. Nickel-containing superoxide dismutase, NiSOD [109770] (1)
    22. Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain [109775] (1)
        contains extra alpha+beta subdomain formed by the N- and C-termini.
    23. Domain from hypothetical 2610208m17rik protein [109779] (1)
    24. TrmE connector domain [116878] (1)
    25. YppE-like [140415] (1)
        flattened bundle at one end with helices 2 and coming in contact and separating helices 1 and 3
    26. MW0975(SA0943)-like [140423] (1)
        open bundle; there is a long groove between helices 1 and 4
    27. VPS28 C-terminal domain-like [140427] (1)
35. PTS-regulatory domain, PRD [63519] (1)
    core: 4 helices; bundle, closed, right-handed twist; 1 crossover connection
    1. PTS-regulatory domain, PRD [63520] (1)
       duplication: consists of two domains of this fold
36. Ferritin-like [47239] (4)
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
    1. Ferritin-like [47240] (5)
       contains bimetal-ion centre in the middle of the bundle
    2. Cobalamin adenosyltransferase-like [89028] (2)
       crossover loop goes across a different side of the 4-helical bundle; no internal metal-binding site
    3. EsxAB dimer-like [140453] (1)
       (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals
    4. PE/PPE dimer-like [140459] (2)
       (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals inside the bundle
37. 4-helical cytokines [47265] (1)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
    1. 4-helical cytokines [47266] (3)
       there are two different topoisomers of this fold with different entanglements of the two crossover connections
38. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1)
    core: 4 helices; bundle; one loop crosses over one side of the bundle
    1. Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323] (1)
39. Acyl carrier protein-like [47335] (3)
    4 helices, bundle; helix 3 is shorter than others; up-and-down
    1. ACP-like [47336] (3)
    2. Colicin E immunity proteins [47345] (1)
    3. Retrovirus capsid dimerization domain-like [47353] (2)
40. Bromodomain-like [47363] (10)
    4 helices; bundle; minor mirror variant of up-and-down topology
    1. Bromodomain [47370] (1)
    2. alpha-ketoacid dehydrogenase kinase, N-terminal domain [69012] (1)
    3. Acyl-CoA dehydrogenase C-terminal domain-like [47203] (2)
       multidomain flavoprotein; N-terminal domain is all-alpha; the middle domain is open (5,8) barrel
    4. Plant invertase/pectin methylesterase inhibitor [101148] (1)
       contains a short alpha-hairpin at the N-terminal extension
    5. Mob1/phocein [101152] (1)
       common fold is elaborated with additional short helices; contains a zinc-binding site
    6. Bacteriocin immunity protein-like [109797] (2)
    7. LemA-like [140478] (1)
       helices 2 and 3 are shorther than helices 1 and 4
    8. MAST3 pre-PK domain-like [140482] (1)
       this domain precedes the Protein Kinase domain in Microtubule-associated serine/threonine-protein kinase 3 (MAST3)
    9. PA2201 N-terminal domain-like [140486] (1)
    10. Nqo1C-terminal domain-like [140490] (1)
        contains extra C-terminal helix that caps the bundle at one end and Fe4-S4 cluster at the other end
41. ROP-like [47379] (8)
    4 helices; dimer of identical alpha-hairpin subunits; bundle, closed, left-handed twist
    1. ROP protein [47380] (1)
    2. Homodimeric domain of signal transducing histidine kinase [47384] (1)
    3. Nonstructural protein ns2, Nep, M1-binding domain [101156] (1)
    4. Dimerisation domain of CENP-B [101160] (1)
    5. Hypothetical protein D-63 [109801] (1)
    6. HP1531-like [140496] (1)
       contains short extra helix in the loop between the two bundle-forming helices
    7. BAS1536-like [140500] (1)
    8. FHV B2 protein-like [140506] (1)
42. Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit [47390] (1)
    4 helices; bundle, closed, right-handed twist
    1. Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit [47391] (1)
       dimer of identical alpha-hairpin motifs
43. Soluble domain of poliovirus core protein 3a [89042] (1)
    4 helices; bundle, closed, right-handed twist
    1. Soluble domain of poliovirus core protein 3a [89043] (1)
       dimer of identical alpha-hairpin motifs
44. Transcription factor IIA (TFIIA), alpha-helical domain [47395] (1)
    4 helices; bundle, closed, right-handed twist
    1. Transcription factor IIA (TFIIA), alpha-helical domain [47396] (1)
       dimer of non-identical alpha-hairpins
45. Ectatomin subunits [47400] (1)
    4 helices; bundle, closed, left-handed twist
    1. Ectatomin subunits [47401] (1)
       disulfide-linked heterodimer of similar alpha-hairpin subunits
46. Dimerisation interlock [47405] (4)
    4 helices; bundle, closed, right-handed twist
    1. SinR repressor dimerisation domain-like [47406] (1)
       intertwined heterodimer of two homologous chains
    2. Dimerization cofactor of HNF-1 alpha [100957] (1)
    3. Docking domain A of the erythromycin polyketide synthase (DEBS) [101166] (1)
    4. Phenylalanine zipper [109805] (1)
       interlocking dimer with longer helices and aromatic-rich core
47. lambda repressor-like DNA-binding domains [47412] (1)
    core: 4 helices; folded leaf, closed
    1. lambda repressor-like DNA-binding domains [47413] (13)
48. Signal peptide-binding domain [47445] (1)
    4 helices; orthogonal array
    1. Signal peptide-binding domain [47446] (1)
49. A DNA-binding domain in eukaryotic transcription factors [47453] (1)
    4 helices; the long C-terminal helix protrudes from the domain and binds to DNA
    1. A DNA-binding domain in eukaryotic transcription factors [47454] (1)
50. HLH-like [47458] (2)
    4-helices; bundle, closed, left-handed twist; 2 crossover connections
    1. HLH, helix-loop-helix DNA-binding domain [47459] (1)
       dimer of two identical helix-loop-helix subunits
    2. Docking domain B of the erythromycin polyketide synthase (DEBS) [101173] (1)
51. EF Hand-like [47472] (4)
    core: 4 helices; array of 2 hairpins, opened
    1. EF-hand [47473] (11)
       Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
    2. Insect pheromone/odorant-binding proteins [47565] (1)
       the N-terminal extension, containing a few short helices, forms a flexible lid for the binding cavity
    3. Hypothetical protein MTH865 [69025] (1)
    4. Cloroperoxidase [47571] (1)
       duplication: consists of 2 similar domains composed of 2 EF hand-like motifs each
52. CH domain-like [47575] (3)
    core: 4 helices: bundle
    1. Calponin-homology domain, CH-domain [47576] (1)
    2. X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain [81761] (1)
    3. Hook domain [116907] (1)
53. Domain of poly(ADP-ribose) polymerase [47586] (1)
    core: 4 helices: bundle; unusual topology
    1. Domain of poly(ADP-ribose) polymerase [47587] (1)
       duplication: consists of 2 helix-loop-helix structural repeats
54. SWIB/MDM2 domain [47591] (1)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
    1. SWIB/MDM2 domain [47592] (1)
       binds to the transactivation domain of human p53
55. Pre-protein crosslinking domain of SecA [81766] (1)
    core: 4 helices: bundle; flanked by two short beta-hairpins
    duplication: consists of two structural repeats
    1. Pre-protein crosslinking domain of SecA [81767] (1)
56. Ribbon-helix-helix [47597] (1)
    core: 4 helices; array of 2 hairpins, opened
    1. Ribbon-helix-helix [47598] (8)
       formerly Met repressor-like; dimeric proteins; the N-termini form a small beta-sheet ribbon
57. Glutathione S-transferase (GST), C-terminal domain [47615] (1)
    core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix
    1. Glutathione S-transferase (GST), C-terminal domain [47616] (1)
       this domains follows the thioredoxin-like N-terminal domain
58. Methionine synthase domain-like [47643] (3)
    4 helices; bundle, left-handed twist; right-handed superhelix
    1. Methionine synthase domain [47644] (1)
    2. Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain [47648] (1)
    3. TM0693-like [140560] (1)
       helix-swapped dimer; in which the two last helices of this fold form a single coiled-coil helix
59. KaiA/RbsU domain [101214] (1)
    4 helices; bundle, right-handed twist; right-handed superhelix
    1. KaiA/RbsU domain [101215] (2)
60. STAT-like [47654] (6)
    4 long helices; bundle, left-handed twist (coiled coil); right-handed superhelix
    1. STAT [47655] (1)
    2. t-snare proteins [47661] (1)
    3. Cag-Z [109839] (1)
       four-helical bundle without significant twist
    4. CAPPD, an extracellular domain of amyloid beta A4 protein [109843] (1)
       the first three helices are longer than the fourth one and, taken separately, adopt a Spectrin repeat-like fold (scop_cf 46965)
    5. FlgN-like [140566] (1)
       the last helix is shorter than the three others; a short extra helix between helices 2 an 3 fills the gap in the bundle
    6. MukF C-terminal domain-like [140570] (1)
61. N-cbl like [47667] (4)
    4 helices; bundle, left-handed twist; left-handed superhelix
    1. N-terminal domain of cbl (N-cbl) [47668] (1)
    2. Transferrin receptor-like dimerisation domain [47672] (1)
    3. Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 [47676] (1)
    4. HIV integrase-binding domain [140576] (1)
62. Replisome organizer (g39p helicase loader/inhibitor protein) [89063] (1)
    4 helices; bundle, right-handed twist; left-handed superhelix
    1. Replisome organizer (g39p helicase loader/inhibitor protein) [89064] (1)
63. Hypothetical protein YqbG [116914] (1)
    core: 4 helices; bundle, right-handed twist; left-handed superhelix
    1. Hypothetical protein YqbG [116915] (1)
64. C-terminal domain of B transposition protein [47680] (1)
    4 helices; irregular array
    1. C-terminal domain of B transposition protein [47681] (1)
65. HAND domain of the nucleosome remodeling ATPase ISWI [101223] (1)
    4 helices; irregular array
    1. HAND domain of the nucleosome remodeling ATPase ISWI [101224] (1)
66. N-terminal, cytoplasmic domain of anti-sigmaE factor RseA [89068] (1)
    4 helices; irregular array
    1. N-terminal, cytoplasmic domain of anti-sigmaE factor RseA [89069] (1)
67. Anaphylotoxins (complement system) [47685] (1)
    4 helices; irregular array, disulfide-linked
    1. Anaphylotoxins (complement system) [47686] (1)
68. Cytochrome c oxidase subunit h [47693] (1)
    4 helices; irregular array, disulfide-linked
    1. Cytochrome c oxidase subunit h [47694] (1)
69. Crustacean CHH/MIH/GIH neurohormone [81777] (1)
    4 helices; irregular array, disulfide-linked
    1. Crustacean CHH/MIH/GIH neurohormone [81778] (1)
70. C-terminal domain of DFF45/ICAD (DFF-C domain) [81782] (1)
    4 helices; folded leaf; right-handed superhelix
    1. C-terminal domain of DFF45/ICAD (DFF-C domain) [81783] (1)
71. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47698] (1)
    4 helices; folded leaf; right-handed superhelix
    1. Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin [47699] (3)
       can be classified as disulfide-rich
72. p53 tetramerization domain [47718] (1)
    core: 4 helices; bundle
    1. p53 tetramerization domain [47719] (1)
       homotetramer
73. Bcr-Abl oncoprotein oligomerization domain [69035] (1)
    core: 4 long helices; bundle
    1. Bcr-Abl oncoprotein oligomerization domain [69036] (1)
       homotetramer
74. Domain of early E2A DNA-binding protein, ADDBP [47723] (1)
    4 helices; bundle, partly opened
    1. Domain of early E2A DNA-binding protein, ADDBP [47724] (1)
       this domain is the first in the fragment of known structure
75. IHF-like DNA-binding proteins [47728] (1)
    core: 4 helices; bundle, partly opened, capped with a beta-sheet
    1. IHF-like DNA-binding proteins [47729] (2)
       dimer of identical subunits
76. TraM-like [140580] (1)
    multihelical oligomeric protein; structure of whole subunit is not known; the N-terminal part is implicated in DNA binding, the middle region forms tetrameric parallel coiled coil, surrounded by the C-terminal helices
    1. TraM-like [140581] (1)