Structural Classification of Proteins
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Superfamily: EsxAB dimer-like

(hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Ferritin-like [47239]
    core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
  4. Superfamily: EsxAB dimer-like [140453]
    (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals

Families:

  1. ESAT-6 like [140454] (2)
    Pfam 06013; the conserwed WxG motif makes the turn at the alpha-hairpin tip
    1. ESAT-6 like protein EsxB [140455]
      1. Mycobacterium tuberculosis [TaxId: 1773] [140456] (1) picpic
    2. ESAT-6, EsxA [140457]
      6 kDa early secretory antigenic target
      1. Mycobacterium tuberculosis [TaxId: 1773] [140458] (1) picpic
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MRC site Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007
Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk