Structural Classification of Proteins




Protein: Immunoglobulin light chain kappa variable domain, VL-kappa from Mouse (Mus musculus), cluster 4 [TaxId: 10090]
Lineage:
- Root: scop
- Class: All beta proteins [48724]
- Fold: Immunoglobulin-like beta-sandwich [48725]
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
- Superfamily: Immunoglobulin [48726]
- Family: V set domains (antibody variable domain-like) [48727]
- Protein: Immunoglobulin light chain kappa variable domain, VL-kappa [88519]
VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
- Species: Mouse (Mus musculus), cluster 4 [TaxId: 10090] [88531]
PDB Entry Domains:
- 1mqk


part of Fv against Paracoccus denitrificans cytochrome c oxidase
- chain l [85054]


- 1mex




part of Fab 29g12
complexed with rac
- region l:1-107 [91259]


- 1a2y



part of Fv D1.3
complexed with po4; mutant
- chain a [19926]


- 1c5c




part of humanized catalytic Fab 21D8 with a decarboxylase activity
complexed with gol, tk4
- region l:1-107 [20474]


- 1um5




complexed with ss1
- region l:2-109 [113304]


- 1uac



part of Fv HyHEL-10
mutant
- chain l [99133]


- 1vfa


part of Fv D1.3
- chain a [19928]


- 1vfb



part of Fv D1.3
- chain a [19930]


- 1g7j



part of Fv D1.3
mutant
- chain a [19932]


- 1i8k


part of dsFv MR1; complex with a EGFR-VIII peptide
mutant
- chain a [71130]


- 1p7k




part of anti-ssDNA Fab
complexed with 1pe, epe, gol, peg, so4
- region l:1-107 [94293]


- region a:1-107 [94287]


- 2dqd


automatically matched to d3hfml1
mutant
- region l:1-107 [131621]


- 1j1o



part of Fv HyHEL-10
mutant
- chain l [77058]


- 1j1x



part of Fv HyHEL-10
mutant
- chain l [77064]


- 1j1p



part of Fv HyHEL-10
mutant
- chain l [77061]


- 2dqc


automatically matched to d3hfml1
mutant
- region l:1-107 [131619]


- 2dqj



automatically matched to d3hfml1
- region l:1-107 [131636]


- 1kcv




part of anti-hepatitis B Fab pc282
- region l:1-107 [72317]


- 1nby





part of anti-lysozyme Fab HYHEL-63
mutant
- region a:1-107 [85536]


- 1dqq




part of anti-lysozyme Fab HYHEL-63
- region a:1-107 [20420]


- region c:1-107 [20422]


- 1g7i



part of Fv D1.3
complexed with po4; mutant
- chain a [19934]


- 1kiq



part of Fv D1.3
mutant
- chain a [19938]


- 1g7m



part of Fv D1.3
mutant
- chain a [19936]


- 1fns





part of Fab NMC-4 blocking the von willebrand factor (vwf) a1 domain function
mutant
- region l:1-107 [20288]


- 1wej





part of anti-cytochrome c Fab E8
complexed with ace, hem, zn
- region l:1-107 [20360]


- 1n7m




part of metal chelatase catalytic Fab 7G12; germline antibody; chain identifiers are probably mixed up
complexed with mmp
- region h:1-107 [80252]


- 1um4




complexed with sh4
- region l:2-109 [113300]


- 2adf




automatically matched to d1a0ql1
complexed with acy, gol, so4
- region l:2-107 [126586]


- 2dqe


automatically matched to d3hfml1
mutant
- region l:1-107 [131623]


- 1ndg





a part of Fab HYHEL-8, L chain is identical to HYHEL-63
complexed with acy; mutant
- region a:1-107 [85576]


- 1r3j





part of Fab against potassium channel KcsA
complexed with dga, f09, tl; mutant
- region a:1-107 [96928]


- 1a7n


part of Fv D1.3
mutant
- chain l [19940]


- 1xiw




- chain c [115369]


- chain g [115373]


- 1g7h



part of Fv D1.3
mutant
- chain a [19948]


- 1a7r


part of Fv D1.3
mutant
- chain l [19944]


- 1nbz





part of anti-lysozyme Fab HYHEL-63
mutant
- region a:1-107 [85541]


- 1kir



part of Fv D1.3
mutant
- chain a [19946]


- 1a7o


part of Fv D1.3
mutant
- chain l [19942]


- 1dvf



part of Fv E5.2, anti-idiotopic antibody to D1.3
CASP1
complexed with zn
- chain c [20106]


- 1jfq




part of Fab 36-71
- region l:1-108 [66648]


- 1a7p


part of Fv D1.3
complexed with acy; mutant
- chain l [19950]


- 1a7q


part of Fv D1.3
mutant
- chain l [19954]


- 1dvf



part of Fv D1.3
CASP1
complexed with zn
- chain a [19952]


- 1ua6



part of Fv HyHEL-10
mutant
- chain l [99130]


- 1um6




- region l:2-109 [113308]


- 1e4w




part of anti-TGFalpha Fab TAB2
complexed with cl, ni
- region l:1-107 [59234]


- 1k4c





part of Fab against potassium channel KcsA
complexed with dga, f09, k; mutant
- region b:1-107 [68128]


- 1h8n


part of anti-ampicillin scFv
complexed with gol, so4; mutant
- region a:3-109 [60783]


- 1kip



part of Fv D1.3
mutant
- chain a [19956]


- 1g7l



part of Fv D1.3
mutant
- chain a [19958]


- 1p2c





part of anti-lysozyme Fab F10.6.6
- region a:1-107 [93915]


- region d:901-1007 [93920]


- 1osp





part of Fab 184.1 against OspA
mutant
- region l:1-107 [20116]


- 1dqj





part of anti-lysozyme Fab HYHEL-63
- region a:1-107 [20424]


- 12e8




part of Fab 2E8 specific to the low density lipoprotein receptor binding region of apolipoprotein E
- region l:1-107 [20268]


- region m:1-107 [20270]


- 1bm3




part of anti-integrin Fab OPG2
- region l:1-107 [20066]


- 1ic7



part of Fv HyHEL-10
mutant
- chain l [62259]


- 1jgl




part of anti-estradiol Fab 57-2
complexed with est
- region l:1-107 [66681]


- 6fab




part of Fab 36-71
- region l:1-108 [19908]


- 1c5b




part of humanized catalytic Fab 21D8 with a decarboxylase activity
- region l:1-107 [20476]


- 1d5i




part of humanized oxy-cope catalytic Fab az-28
- region l:1-107 [20194]


- 1fe8





part of Fab RU5 inhibiting the collagen binding by the von willebrand factor a3 domain
complexed with cac, fuc, nag
- region l:1-107 [59792]


- region m:1-107 [59794]


- region n:1-107 [59796]


- 1e4x




part of anti-TGFalpha Fab TAB2
- region l:1-107 [59240]


- region m:1-107 [59242]


- 1opg




part of anti-integrin Fab OPG2
- region l:1-107 [20068]


- 1d6v




part of humanized oxy-cope catalytic Fab az-28
- region l:1-107 [20196]


- 1gaf




part of humanized Fab 48G7
complexed with npe
- region l:1-109 [20082]


- 1i8m




part of anti-ssDNA Fab
complexed with so4
- region l:1-107 [66088]


- region a:1-107 [66082]


- 1ndm





a part of Fab HYHEL-26, L chain is identical to HYHEL-63
mutant
- region a:1-107 [85581]


- 2rcs




part of humanized Fab 48G7
- region l:1-109 [20086]


- 1aj7




part of humanized Fab 48G7
complexed with npe
- region l:1-109 [20084]


- 1dzb



part of anti-lysozyme scFv 1F9
- region a:201-307 [20489]


- region b:201-307 [20491]


- 1s5h





complexed with dga, f09, k; mutant
- region a:1-107 [105267]


- 1i8i


part of dsFv MR1; complex with a EGFR-VIII peptide
mutant
- chain a [71128]


- 1ic5



part of Fv HyHEL-10
mutant
- chain l [62255]


- 1mlb




part of Fab D44.1
- region a:1-108 [20050]


- 1k4d





part of Fab against potassium channel KcsA
complexed with dga, f09, k, na; mutant
- region b:1-107 [68133]


- 1emt




part of anti-C60 fullerene Fab
- region l:1-107 [20482]


- 1mlc





part of Fab D44.1
- region a:1-108 [20052]


- region c:1-108 [20054]


- 1oak





part of Fab NMC-4 blocking the von willebrand factor (vwf) a1 domain function
- region l:1-107 [20290]


- 1kcu




part of anti-hepatitis B Fab pc287
- region l:1-107 [72313]


- 1ct8




part of catalytic Fab 7C8
- region a:1-107 [20408]


- region c:1-107 [20410]


- 1i3g


part of anti-ampicillin scFv
complexed with mpd
- chain l [66019]


- 1qbl




part of anti-cytochrome c Fab E8