Protein: Immunoglobulin heavy chain variable domain, VH from Human (Homo sapiens), cluster 3 [TaxId: 9606]

Lineage:

1. Root: scop
2. Class: All beta proteins [48724]
3. Fold: Immunoglobulin-like beta-sandwich [48725]
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands
4. Superfamily: Immunoglobulin [48726]
5. Family: V set domains (antibody variable domain-like) [48727]
6. Protein: Immunoglobulin heavy chain variable domain, VH [88543]
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
7. Species: Human (Homo sapiens), cluster 3 [TaxId: 9606] [88547]

PDB Entry Domains:

1. 8fab
   part of Fab HIL
   1. region b:1-121 [19773]
   2. region d:1-121 [19775]
2. 2fb4
   part of Fab KOL
   1. region h:1-119 [19847]
3. 1aqk
   part of Fab B7-15A2
   1. region h:1-123 [20193]
4. 1w72
   complexed with gol
   1. region h:1-113 [114299]
   2. region i:1-113 [114301]
5. 1nl0
   part of Fab 10c12 against factor IX Gla domain
   complexed with ca, so4
   1. region h:1-113 [91945]
6. 1zls
   automatically matched to d1aqkh1
   complexed with man
   1. region h:1-112 [125255]
7. 1zlv
   automatically matched to d1aqkh1
   complexed with man
   1. region h:1-112 [125262]
8. 1zlv
   automatically matched to d1aqkh1
   complexed with man
   1. region m:1-112 [125264]
9. 1igm
   part of IgM Fv POT
   1. chain h [19827]
10. 1dql
    part of IgM Fv MEZ
    1. chain h [19829]
11. 1y0l
    automatically matched to d1aqkh1
    complexed with cl, han
    1. region b:1-113 [122488]
12. 1y0l
    automatically matched to d1aqkh1
    complexed with cl, han
    1. region d:1-113 [122492]
13. 1y0l
    automatically matched to d1aqkh1
    complexed with cl, han
    1. region f:1-113 [122496]
14. 1y0l
    automatically matched to d1aqkh1
    complexed with cl, han
    1. region h:1-113 [122498]
15. 1dfb
    part of Fab 3D6
    1. region h:1-126 [19811]
16. 1dee
    part of IgM RF 2A2
    1. region b:501-621 [20443]
    2. region d:1501-1621 [20445]
    3. region f:2501-2621 [20447]
17. 1hez
    part of IgM RF 2A2
    complexed with imd
    1. region b:1-121 [60985]
    2. region d:1-121 [60989]
18. 1u6a
    automatically matched to d1aqkh1
    1. region h:2-113 [119564]
19. 1y18
    automatically matched to d1aqkh1
    complexed with cl, han; mutant
    1. region b:1-113 [122523]
20. 1y18
    automatically matched to d1aqkh1
    complexed with cl, han; mutant
    1. region d:1-113 [122527]
21. 1y18
    automatically matched to d1aqkh1
    complexed with cl, han; mutant
    1. region f:1-113 [122531]
22. 1y18
    automatically matched to d1aqkh1
    complexed with cl, han; mutant
    1. region h:1-113 [122533]
23. 1zlw
    automatically matched to d1aqkh1
    complexed with bma, man
    1. region h:1-112 [125266]
24. 1zlw
    automatically matched to d1aqkh1
    complexed with bma, man
    1. region m:1-112 [125268]
25. 1zlu
    automatically matched to d1aqkh1
    complexed with man
    1. region h:1-112 [125258]
26. 1zlu
    automatically matched to d1aqkh1
    complexed with man
    1. region m:1-112 [125260]
27. 2ig2
    part of antibody KOL; intact protein but only Fab's can be seen in the crystal structure
    1. region h:1-119 [19849]
28. 1adq
    part of IgM rheumatoid factor Fab
    1. region h:1-113 [20273]

Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007 Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk