Structural Classification of Proteins
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Protein: Immunoglobulin light chain kappa variable domain, VL-kappa from Human (Homo sapiens), cluster 3.1 [TaxId: 9606]

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
  5. Family: V set domains (antibody variable domain-like) [48727]
  6. Protein: Immunoglobulin light chain kappa variable domain, VL-kappa [88519]
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. Species: Human (Homo sapiens), cluster 3.1 [TaxId: 9606] [88522]

PDB Entry Domains:

  1. 1n0x picpicxrefxrefxref
    part of an anti HIV-1 Fab
    complexed with cxs, gol, k, orn, so4
    1. region l:1-107 [91532] picpiclink
    2. region m:1-107 [91534] picpiclink
  2. 2brr picpicxrefxrefxrefxref
    automatically matched to d1hzhl1
    complexed with acy, nh2, so4
    1. region l:1-107 [129011] picpiclink
  3. 2brr picpicxrefxrefxrefxref
    automatically matched to d1hzhl1
    complexed with acy, nh2, so4
    1. region x:2-107 [129013] picpiclink
  4. 1iqd picpicxrefxrefxrefxref
    part of Fab BO2C11 against the C2 domain of factor VIII
    mutant
    1. region a:2-108 [62644] picpiclink
  5. 1dn0 picpicxrefxrefxref
    part of Fab Kau cold agglutinin IgM
    1. region a:1-107 [19830] picpiclink
    2. region c:1-107 [19832] picpiclink
  6. 2ny7 picpicxrefxrefxref
    automatically matched to d1hzhl1
    complexed with nag; mutant
    1. region l:1-107 [138802] picpiclink
  7. 1qlr picpicxrefxrefxref
    part of Fab Kau cold agglutinin IgM
    complexed with fuc, nag
    1. region a:1-107 [19834] picpiclink
    2. region c:1-107 [19836] picpiclink
  8. 1hzh picpicxrefxrefxrefxrefxref
    part of intact IgG B12 antibody
    complexed with fuc, gal, man, nag
    1. region l:1-107 [61445] picpiclink
    2. region m:1-107 [61447] picpiclink
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MRC site Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007
Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk