Protein: Immunoglobulin light chain kappa variable domain, VL-kappa from Human (Homo sapiens), cluster 3.2 [TaxId: 9606]

Lineage:

1. Root: scop
2. Class: All beta proteins [48724]
3. Fold: Immunoglobulin-like beta-sandwich [48725]
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands
4. Superfamily: Immunoglobulin [48726]
5. Family: V set domains (antibody variable domain-like) [48727]
6. Protein: Immunoglobulin light chain kappa variable domain, VL-kappa [88519]
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
7. Species: Human (Homo sapiens), cluster 3.2 [TaxId: 9606] [88523]

PDB Entry Domains:

1. 2fx7
   automatically matched to d1rhha1
   complexed with gol; mutant
   1. region l:1-107 [134278]
2. 2nxy
   automatically matched to d1g9ml1
   complexed with hez, nag, trs; mutant
   1. region c:2001-2109 [138747]
3. 2ny2
   automatically matched to d1g9ml1
   complexed with edo, hez, nag, suc; mutant
   1. region c:2001-2109 [138772]
4. 2ny3
   automatically matched to d1g9ml1
   complexed with nag, suc; mutant
   1. region c:2001-2109 [138778]
5. 2ny4
   automatically matched to d1g9ml1
   complexed with hez, nag, suc; mutant
   1. region c:2001-2109 [138784]
6. 1rhh
   part of HIV-1 neutralizing Fab x5
   1. region a:1-106a [97473]
   2. region c:1-106a [97477]
7. 2ny1
   automatically matched to d1g9ml1
   complexed with nag, suc; mutant
   1. region c:2001-2109 [138766]
8. 2nxz
   automatically matched to d1g9ml1
   complexed with edo, hez, ipa, nag, suc; mutant
   1. region c:2001-2109 [138753]
9. 2fx9
   automatically matched to d1rhha1
   complexed with orq
   1. region l:1-107 [134300]
10. 2fx9
    automatically matched to d1rhha1
    complexed with orq
    1. region m:1-107 [134302]
11. 1tzg
    automatically matched to d1rhha1
    complexed with gol
    1. region l:1-107 [119400]
12. 1tzg
    automatically matched to d1rhha1
    complexed with gol
    1. region m:1-107 [119402]
13. 2ny0
    automatically matched to d1g9ml1
    complexed with hez, nag; mutant
    1. region c:2001-2109 [138760]
14. 2fx8
    automatically matched to d1rhha1
    mutant
    1. region l:1-107 [134288]
15. 2fx8
    automatically matched to d1rhha1
    mutant
    1. region m:1-107 [134290]
16. 2fx8
    automatically matched to d1rhha1
    mutant
    1. region n:1-107 [134292]
17. 2fx8
    automatically matched to d1rhha1
    mutant
    1. region o:1-107 [134294]
18. 1yym
    automatically matched to d1g9ml1
    complexed with edo, ipa, mpt, nag, ndg, vlm; mutant
    1. region l:1-107 [124235]
19. 1yym
    automatically matched to d1g9ml1
    complexed with edo, ipa, mpt, nag, ndg, vlm; mutant
    1. region q:1001-1107 [124238]
20. 1rz8
    part of anti HIV-1 gp120 Fab 17B
    1. region a:1-109 [98137]
    2. region c:1-109 [98141]
21. 1y0l
    automatically matched to d1g9ml1
    complexed with cl, han
    1. region a:1-107 [122486]
22. 1y0l
    automatically matched to d1g9ml1
    complexed with cl, han
    1. region c:1-107 [122490]
23. 1y0l
    automatically matched to d1g9ml1
    complexed with cl, han
    1. region e:1-107 [122494]
24. 1y0l
    automatically matched to d1g9ml1
    complexed with cl, han
    1. region l:1-107 [122500]
25. 2i60
    automatically matched to d1g9ml1
    complexed with ipa, mpt, nag, ndg, vlm
    1. region l:1-107 [137084]
26. 2i60
    automatically matched to d1g9ml1
    complexed with ipa, mpt, nag, ndg, vlm
    1. region q:1-107 [137087]
27. 2ny5
    automatically matched to d1g9ml1
    complexed with nag, suc; mutant
    1. region l:2001-2109 [138792]
28. 1g9m
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with fuc, ioh, nag; mutant
    1. region l:1-109 [20262]
29. 1rzj
    part of anti HIV-1 gp120 Fab 17B
    complexed with fuc, ioh, nag; mutant
    1. region l:1-109 [98203]
30. 1gc1
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with fuc, nag; mutant
    1. region l:1-109 [20264]
31. 1yyl
    automatically matched to d1g9ml1
    complexed with bif, mpt, nag, ndg, vlm; mutant
    1. region l:1-107 [124225]
32. 1yyl
    automatically matched to d1g9ml1
    complexed with bif, mpt, nag, ndg, vlm; mutant
    1. region q:1001-1107 [124228]
33. 1u6a
    automatically matched to d1rhha1
    1. region l:1-107 [119566]
34. 2agj
    automatically matched to d1rhha1
    complexed with nag
    1. region l:1-108 [126727]
35. 2ny6
    automatically matched to d1g9ml1
    complexed with nag, suc; mutant
    1. region c:2001-2109 [138796]
36. 2i5y
    automatically matched to d1g9ml1
    complexed with bif, mpt, nag, ndg, vlm
    1. region l:1-107 [137074]
37. 1y18
    automatically matched to d1g9ml1
    complexed with cl, han; mutant
    1. region a:1-107 [122521]
38. 1y18
    automatically matched to d1g9ml1
    complexed with cl, han; mutant
    1. region c:1-107 [122525]
39. 1y18
    automatically matched to d1g9ml1
    complexed with cl, han; mutant
    1. region e:1-107 [122529]
40. 1y18
    automatically matched to d1g9ml1
    complexed with cl, han; mutant
    1. region l:1-107 [122535]
41. 2i5y
    automatically matched to d1g9ml1
    complexed with bif, mpt, nag, ndg, vlm
    1. region q:1-107 [137077]
42. 1rzk
    part of anti HIV-1 gp120 Fab 17B
    complexed with nag; mutant
    1. region l:1-109 [98210]
43. 1g9n
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with nag; mutant
    1. region l:1-109 [20266]
44. 2b4c
    automatically matched to d1rhha1
    complexed with fuc, nag, ndg, so4, xyl; mutant
    1. region l:1-107 [127824]

Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007 Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk