Structural Classification of Proteins
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Protein: Immunoglobulin light chain kappa constant domain, CL-kappa from Human (Homo sapiens) [TaxId: 9606]

including humanized antibodies (chimeric proteins with human constant domains)

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
  5. Family: C1 set domains (antibody constant domain-like) [48942]
  6. Protein: Immunoglobulin light chain kappa constant domain, CL-kappa [88566]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [88569]
    including humanized antibodies (chimeric proteins with human constant domains)

PDB Entry Domains:

  1. 1c5c picpicxrefxrefxref
    part of humanized catalytic Fab 21D8 with a decarboxylase activity
    complexed with gol, tk4
    1. region l:108-214 [21438] picpiclink
  2. 1um5 picpicxrefxrefxref
    complexed with ss1
    1. region l:110-217 [113305] picpiclink
  3. 1jpt picpicxrefxrefxref
    part of humanized Fab D3H44 against human tissue factor
    1. region l:108-213 [67054] picpiclink
  4. 1l7i picpicxrefxrefxref
    part of humanized anti-ERBb2 Fab 2C4
    complexed with so4
    1. region l:108-214 [73659] picpiclink
  5. 1n0x picpicxrefxrefxref
    part of an anti HIV-1 Fab
    complexed with cxs, gol, k, orn, so4
    1. region l:108-214 [91533] picpiclink
    2. region m:108-214 [91535] picpiclink
  6. 1jps picpicxrefxrefxrefxref
    part of humanized Fab D3H44 against human tissue factor
    1. region l:108-213 [67048] picpiclink
  7. 1n7m picpicxrefxrefxref
    part of metal chelatase catalytic Fab 7G12; germline antibody; chain identifiers are probably mixed up
    complexed with mmp
    1. region h:108-213 [80253] picpiclink
  8. 1um4 picpicxrefxrefxref
    complexed with sh4
    1. region l:110-217 [113301] picpiclink
  9. 1op3 picpicxrefxrefxref
    part of Fab 2G12
    complexed with box, man
    1. region k:108-212 [87211] picpiclink
    2. region l:108-212 [87213] picpiclink
  10. 1t3f picpicxrefxrefxref
    1. region a:109-214 [112229] picpiclink
  11. 1rzg picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 412D
    complexed with suc
    1. region b:108-213 [98157] picpiclink
    2. region d:108-214 [98161] picpiclink
  12. 1rz7 picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 48D
    complexed with gol
    1. region l:108-213 [98136] picpiclink
  13. 1um6 picpicxrefxrefxref
    1. region l:110-217 [113309] picpiclink
  14. 1tjg picpicxrefxrefxref
    complexed with egl, ioh, ycm
    1. region l:108-214 [112449] picpiclink
  15. 1iqd picpicxrefxrefxrefxref
    part of Fab BO2C11 against the C2 domain of factor VIII
    mutant
    1. region a:109-212 [62645] picpiclink
  16. 1vge picpicxrefxrefxref
    part of humanized Fab TR1.9
    1. region l:108-214 [21126] picpiclink
  17. 1rhh picpicxrefxrefxref
    part of HIV-1 neutralizing Fab x5
    1. region a:107-213 [97474] picpiclink
    2. region c:107-213 [97478] picpiclink
  18. 1ce1 picpicxrefxrefxref
    part of humanized therapeutic antibody CAMPATH-1H
    1. region l:108-211 [21310] picpiclink
  19. 1c5b picpicxrefxrefxref
    part of humanized catalytic Fab 21D8 with a decarboxylase activity
    1. region l:108-214 [21440] picpiclink
  20. 2f5b picpicxrefxrefxref
    part of HIV-1 neutralizing Fab 2F5
    1. region l:108-214 [88509] picpiclink
  21. 1d5i picpicxrefxrefxref
    part of humanized oxy-cope catalytic Fab az-28
    1. region l:108-211 [21210] picpiclink
  22. 1gaf picpicxrefxrefxref
    part of humanized Fab 48G7
    complexed with npe
    1. region l:110-214 [21114] picpiclink
  23. 1d6v picpicxrefxrefxref
    part of humanized oxy-cope catalytic Fab az-28
    1. region l:108-211 [21212] picpiclink
  24. 2f5a picpicxrefxrefxref
    part of HIV-1 neutralizing Fab 2F5
    1. region l:108-213 [88505] picpiclink
  25. 1aj7 picpicxrefxrefxref
    part of humanized Fab 48G7
    complexed with npe
    1. region l:110-214 [21116] picpiclink
  26. 2rcs picpicxrefxrefxref
    part of humanized Fab 48G7
    1. region l:110-214 [21118] picpiclink
  27. 1fl5 picpicxrefxrefxref
    part of humanized catalytic Fab 28b4 with a sulfide oxidase activity
    complexed with so4; mutant
    1. region l:108-212 [65022] picpiclink
    2. region a:108-212 [65016] picpiclink
  28. 1dn0 picpicxrefxrefxref
    part of Fab Kau cold agglutinin IgM
    1. region a:108-215 [20934] picpiclink
    2. region c:108-215 [20936] picpiclink
  29. 1om3 picpicxrefxrefxref
    part of Fab 2G12
    1. region l:108-213 [87064] picpiclink
    2. region m:108-213 [87066] picpiclink
  30. 3fct picpicxrefxrefxref
    part of metal chelatase catalytic Fab 7G12; mature antibody
    complexed with ca, cd, mg, mmp, na
    1. region a:108-213 [21366] picpiclink
    2. region c:108-213 [21368] picpiclink
  31. 1i7z picpicxrefxrefxref
    part of humanized Fab GNC92H2
    complexed with coc
    1. region a:108-214 [61920] picpiclink
    2. region c:108-214 [61924] picpiclink
  32. 1fvd picpicxrefxrefxref
    part of humanized Fab 4D5, herceptin
    1. region a:108-214 [20962] picpiclink
    2. region c:108-214 [20964] picpiclink
  33. 1bj1 picpicxrefxrefxrefxref
    part of humanized Fab-12 neutralizing VEGF
    complexed with so4
    1. region l:108-213 [21314] picpiclink
    2. region j:108-213 [21316] picpiclink
  34. 1bz7 picpicxrefxrefxref
    part of humanized Fab R24 from murine ascites
    1. region a:108-206 [21374] picpiclink
  35. 1a4j picpicxrefxrefxref
    part of humanized Diels-Alder catalytic Fab
    1. region l:113-217 [21242] picpiclink
    2. region a:113-217 [21244] picpiclink
  36. 1rz8 picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 17B
    1. region a:110-212 [98138] picpiclink
    2. region c:110-212 [98142] picpiclink
  37. 1ad0 picpicxrefxrefxref
    part of humanized Fab A5B7
    1. region a:108-213 [21154] picpiclink
    2. region c:108-213 [21156] picpiclink
  38. 1ucb picpicxrefxrefxref
    part of humanized Fab CBR96
    complexed with so4
    1. region l:109-214 [21132] picpiclink
  39. 1cz8 picpicxrefxrefxrefxref
    part of humanized Fab-12 neutralizing VEGF; affinity matured
    complexed with so4; mutant
    1. region l:108-213 [21318] picpiclink
    2. region x:108-213 [21320] picpiclink
  40. 1tjh picpicxrefxrefxref
    complexed with ace, egl, ioh, nh2, ycm
    1. region l:108-214 [112453] picpiclink
  41. 1hkl picpicxrefxrefxref
    part of humanized Fab 48G7
    1. region l:110-214 [21120] picpiclink
  42. 1pg7 picpicxrefxrefxrefxrefxrefxrefxref
    part of humanized Fab D3H44 against human tissue factor
    1. region l:108-213 [94679] picpiclink
    2. region m:108-213 [94681] picpiclink
  43. 1a4k picpicxrefxrefxref
    part of humanized Diels-Alder catalytic Fab
    complexed with cd, fra
    1. region l:113-212 [21246] picpiclink
    2. region a:113-211 [21248] picpiclink
  44. 1g9m picpicxrefxrefxrefxrefxrefxref
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with fuc, ioh, nag; mutant
    1. region l:110-214 [21262] picpiclink
  45. 1fve picpicxrefxrefxref
    part of humanized Fab 4D5, herceptin
    1. region a:108-214 [20966] picpiclink
    2. region c:108-214 [20968] picpiclink
  46. 1mim picpicxrefxrefxref
    part of CD25-binding humanized Fab CHI621
    1. region l:106-210 [21158] picpiclink
  47. 1dfb picpicxrefxrefxref
    part of Fab 3D6
    1. region l:107-212 [20920] picpiclink
  48. 1u8i picpicxrefxrefxref
    1. region a:108-214 [113133] picpiclink
  49. 1tzh picpicxrefxrefxrefxref
    1. region a:108-211 [107478] picpiclink
    2. region l:108-211 [107484] picpiclink
  50. 1rzj picpicxrefxrefxrefxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 17B
    complexed with fuc, ioh, nag; mutant
    1. region l:110-212 [98204] picpiclink
  51. 1b6d picpicxref
    part of Bence-Jones protein DEL
    1. region a:108-212 [21510] picpiclink
    2. region b:108-212 [21511] picpiclink
  52. 1tji picpicxrefxrefxref
    complexed with egl, ioh, nh2, ycm
    1. region l:108-214 [112457] picpiclink
  53. 1gc1 picpicxrefxrefxrefxrefxrefxref
    part of HIV-1 neutralizing Fab 17B; binds to the CD4-induced state of gp120
    complexed with fuc, nag; mutant
    1. region l:110-213 [21264] picpiclink
  54. 1u8h picpicxrefxrefxref
    1. region a:108-214 [113129] picpiclink
  55. 1hez picpicxrefxrefxrefxref
    part of IgM RF 2A2
    complexed with imd
    1. region a:108-214 [60984] picpiclink
    2. region c:108-214 [60988] picpiclink
  56. 1dee picpicxrefxrefxrefxref
    part of IgM RF 2A2
    1. region a:108-214 [21408] picpiclink
    2. region c:1108-1214 [21410] picpiclink
    3. region e:2108-2214 [21412] picpiclink
  57. 1n8z picpicxrefxrefxrefxrefxref
    part of humanized Fab 4D5, herceptin
    complexed with nag, so4
    1. region a:108-214 [80319] picpiclink
  58. 1cly picpicxrefxrefxref
    part of humanized Fab CBR96
    complexed with fuc, gal, nag, non
    1. region l:109-214 [21134] picpiclink
  59. 1u95 picpicxrefxrefxref
    1. region a:108-214 [113229] picpiclink
  60. 1axs picpicxrefxrefxref
    part of humanized oxy-cope catalytic Fab az-28
    complexed with cd, hop
    1. region l:108-211 [21214] picpiclink
    2. region a:108-211 [21216] picpiclink
  61. 1fl6 picpicxrefxrefxref
    part of humanized catalytic Fab 28b4 with a sulfide oxidase activity
    complexed with aah; mutant
    1. region l:108-212 [65030] picpiclink
    2. region a:108-212 [65024] picpiclink
  62. 1mhp picpicxrefxrefxrefxrefxrefxref
    part of humanized anti-alpha1 integrin I-domain Fab
    complexed with mn; mutant
    1. region l:107-213 [84970] picpiclink
  63. 2fgw picpicxrefxrefxref
    part of humanized Fab H52
    1. region l:109-214 [20956] picpiclink
  64. 1b2w picpicxrefxrefxref
    part of a humanized anti-gamma-interferon Fab
    1. region l:108-214 [21298] picpiclink
  65. 1ad9 picpicxrefxrefxref
    part of humanized Fab CTM01
    complexed with so4
    1. region l:108-213 [21224] picpiclink
    2. region a:108-213 [21226] picpiclink
  66. 1uwg picpicxrefxrefxref
    part of catalytic Fab 14d9
    complexed with kha, po4
    1. region l:108-213 [100118] picpiclink
    2. region x:108-213 [100120] picpiclink
  67. 1u8k picpicxrefxrefxref
    1. region a:108-214 [113141] picpiclink
  68. 1u8j picpicxrefxrefxref
    1. region a:108-214 [113137] picpiclink
  69. 1hzh picpicxref