Structural Classification of Proteins
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Protein: Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma from Human (Homo sapiens) [TaxId: 9606]

including humanized antibodies (chimeric proteins with human constant domains)

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
  5. Family: C1 set domains (antibody constant domain-like) [48942]
  6. Protein: Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574]
  7. Species: Human (Homo sapiens) [TaxId: 9606] [88575]
    including humanized antibodies (chimeric proteins with human constant domains)

PDB Entry Domains:

  1. 1c5c picpicxrefxrefxref
    part of humanized catalytic Fab 21D8 with a decarboxylase activity
    complexed with gol, tk4
    1. region h:114-230 [21439] picpiclink
  2. 1um5 picpicxrefxrefxref
    complexed with ss1
    1. region h:120-219 [113303] picpiclink
  3. 1rzf picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab E51
    complexed with gol, ioh
    1. region h:114-214 [98151] picpiclink
  4. 2fx7 picpicxrefxrefxref
    automatically matched to d1ngzb2
    complexed with gol; mutant
    1. region h:114-228 [134277] picpiclink
  5. 1jpt picpicxrefxrefxref
    part of humanized Fab D3H44 against human tissue factor
    1. region h:118-217 [67052] picpiclink
  6. 1l7i picpicxrefxrefxref
    part of humanized anti-ERBb2 Fab 2C4
    complexed with so4
    1. region h:114-216 [73657] picpiclink
  7. 8fab picpicxrefxrefxref
    part of Fab HIL
    1. region b:122-223 [20883] picpiclink
    2. region d:122-222 [20885] picpiclink
  8. 1n0x picpicxrefxrefxref
    part of an anti HIV-1 Fab
    complexed with cxs, gol, k, orn, so4
    1. region h:114-228 [91529] picpiclink
    2. region k:114-230 [91531] picpiclink
  9. 1n7m picpicxrefxrefxref
    part of metal chelatase catalytic Fab 7G12; germline antibody; chain identifiers are probably mixed up
    complexed with mmp
    1. region l:115-216 [80255] picpiclink
  10. 1jps picpicxrefxrefxrefxref
    part of humanized Fab D3H44 against human tissue factor
    1. region h:118-217 [67046] picpiclink
  11. 1um4 picpicxrefxrefxref
    complexed with sh4
    1. region h:120-219 [113299] picpiclink
  12. 1op3 picpicxrefxrefxref
    part of Fab 2G12
    complexed with box, man
    1. region h:116-228 [87209] picpiclink
    2. region m:116-228 [87215] picpiclink
  13. 1t3f picpicxrefxrefxref
    1. region b:119-219 [112231] picpiclink
  14. 2nxy picpicxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with hez, nag, trs; mutant
    1. region d:3129-3229 [138750] picpiclink
  15. 7fab picpicxrefxrefxref
    part of Fab NEW
    1. region h:117-217 [20887] picpiclink
  16. 1aqk picpicxrefxrefxref
    part of Fab B7-15A2
    1. region h:124-226 [21209] picpiclink
  17. 2fb4 picpicxrefxrefxref
    part of Fab KOL
    1. region h:120-221 [20951] picpiclink
  18. 1rz7 picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 48D
    complexed with gol
    1. region h:114-213 [98134] picpiclink
  19. 1rzg picpicxrefxrefxref
    part of anti HIV-1 gp120-reactive Fab 412D
    complexed with suc
    1. region a:114-214 [98155] picpiclink
    2. region c:114-213 [98159] picpiclink
  20. 1um6 picpicxrefxrefxref
    1. region h:120-219 [113307] picpiclink
  21. 1tjg picpicxrefxrefxref
    complexed with egl, ioh, ycm
    1. region h:114-216 [112447] picpiclink
  22. 2hff picpicxrefxref
    automatically matched to d1ngzb2
    1. region b:114-214 [136380] picpiclink
  23. 2ny2 picpicxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with edo, hez, nag, suc; mutant
    1. region d:3129-3228 [138775] picpiclink
  24. 2hff picpicxrefxref
    automatically matched to d1ngzb2
    1. region h:114-213 [136382] picpiclink
  25. 1vge picpicxrefxrefxref
    part of humanized Fab TR1.9
    1. region h:123-225 [21127] picpiclink
  26. 1iqd picpicxrefxrefxrefxref
    part of Fab BO2C11 against the C2 domain of factor VIII
    mutant
    1. region b:115-212 [62647] picpiclink
  27. 2ny3 picpicxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with nag, suc; mutant
    1. region d:3129-3229 [138781] picpiclink
  28. 2ny4 picpicxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with hez, nag, suc; mutant
    1. region d:3129-3229 [138787] picpiclink
  29. 1w72 picpicxrefxrefxrefxrefxrefxref
    complexed with gol
    1. region h:114-228 [114300] picpiclink
    2. region i:114-228 [114302] picpiclink
  30. 1rhh picpicxrefxrefxref
    part of HIV-1 neutralizing Fab x5
    1. region b:114-216 [97476] picpiclink
    2. region d:114-216 [97480] picpiclink
  31. 1ce1 picpicxrefxrefxref
    part of humanized therapeutic antibody CAMPATH-1H
    1. region h:122-220 [21311] picpiclink
  32. 1tjh picpicxrefxrefxref
    complexed with ace, egl, ioh, nh2, ycm
    1. region h:114-216 [112451] picpiclink
  33. 2b1h picpicxref
    automatically matched to d1ngzb2
    1. region h:114-229 [127669] picpiclink
  34. 2f5b picpicxrefxrefxref
    part of HIV-1 neutralizing Fab 2F5
    1. region h:133-235 [88507] picpiclink
  35. 1c5b picpicxrefxrefxref
    part of humanized catalytic Fab 21D8 with a decarboxylase activity
    1. region h:114-230 [21441] picpiclink
  36. 1tji picpicxrefxrefxref
    complexed with egl, ioh, nh2, ycm
    1. region h:114-216 [112455] picpiclink
  37. 2ny1 picpicxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with nag, suc; mutant
    1. region d:3129-3229 [138769] picpiclink
  38. 1d5i picpicxrefxrefxref
    part of humanized oxy-cope catalytic Fab az-28
    1. region h:114-214 [21211] picpiclink
  39. 1u8i picpicxrefxrefxref
    1. region b:114-216 [113135] picpiclink
  40. 2nxz picpicxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with edo, hez, ipa, nag, suc; mutant
    1. region d:3129-3229 [138756] picpiclink
  41. 1d6v picpicxrefxrefxref
    part of humanized oxy-cope catalytic Fab az-28
    1. region h:114-214 [21213] picpiclink
  42. 1gaf picpicxrefxrefxref
    part of humanized Fab 48G7
    complexed with npe
    1. region h:115-217 [21115] picpiclink
  43. 1u8h picpicxrefxrefxref
    1. region b:114-216 [113131] picpiclink
  44. 1aj7 picpicxrefxrefxref
    part of humanized Fab 48G7
    complexed with npe
    1. region h:115-216 [21117] picpiclink
  45. 2rcs picpicxrefxrefxref
    part of humanized Fab 48G7
    1. region h:115-216 [21119] picpiclink
  46. 2f5a picpicxrefxrefxref
    part of HIV-1 neutralizing Fab 2F5
    1. region h:133-232 [88503] picpiclink
  47. 2pr4 picpicxref
    automatically matched to d2f5ah2
    1. region h:133-232 [139749] picpiclink
  48. 2fx9 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with orq
    1. region h:114-227 [134297] picpiclink
  49. 2fx9 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with orq
    1. region i:114-227 [134299] picpiclink
  50. 1u95 picpicxrefxrefxref
    1. region b:114-216 [113231] picpiclink
  51. 1tzg picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with gol
    1. region h:114-232 [119397] picpiclink
  52. 1tzg picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with gol
    1. region i:114-228 [119399] picpiclink
  53. 2ny0 picpicxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with hez, nag; mutant
    1. region d:3129-3229 [138763] picpiclink
  54. 1fl5 picpicxrefxrefxref
    part of humanized catalytic Fab 28b4 with a sulfide oxidase activity
    complexed with so4; mutant
    1. region h:114-213 [65020] picpiclink
    2. region b:114-213 [65018] picpiclink
  55. 2b0s picpicxref
    automatically matched to d1ngzb2
    complexed with acy, edo
    1. region h:114-229 [127647] picpiclink
  56. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    mutant
    1. region h:114-227 [134281] picpiclink
  57. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    mutant
    1. region i:114-227 [134283] picpiclink
  58. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    mutant
    1. region j:114-227 [134285] picpiclink
  59. 2fx8 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    mutant
    1. region k:114-227 [134287] picpiclink
  60. 1yym picpicxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with edo, ipa, mpt, nag, ndg, vlm; mutant
    1. region h:114-214 [124234] picpiclink
  61. 1yym picpicxrefxrefxrefxrefxrefxrefxrefxref
    automatically matched to d1ngzb2
    complexed with edo, ipa, mpt, nag, ndg, vlm; mutant
    1. region r:1114-1214 [124241] picpiclink
  62. 1nl0 picpicxrefxrefxrefxref
    part of Fab 10c12 against factor IX Gla domain
    complexed with ca, so4
    1. region h:114-217 [91946] picpiclink
  63. 1u8k picpicxrefxrefxref
    1. region b:114-215 [113143] picpiclink
  64. 1u8j picpicxrefxrefxref
    1. region b:114-216 [113139] picpiclink
  65. 3fct picpicxrefxrefxref
    part of metal chelatase catalytic Fab 7G12; mature antibody
    complexed with ca, cd, mg, mmp, na
    1. region b:115-216 [21367] picpiclink
    2. region d:115-216 [21369] picpiclink
  66. 1om3 picpicxrefxrefxref
    part of Fab 2G12
    1. region h:116-228 [87060] picpiclink
    2. region k:116-229 [87062] picpiclink
  67. 1u92 picpicxrefxrefxref
    1. region b:114-215 [113223] picpiclink
  68. 1u91 picpicxrefxrefxref
    1. region b:114-216 [113219] picpiclink
  69. 1u8q picpicxrefxrefxref
    1. region b:114-216 [113167] picpiclink
  70. 2ny7 picpicxrefxrefxref
    automatically matched to d1ngzb2
    complexed with nag; mutant
    1. region h:114-230 [138801] picpiclink
  71. 1i7z picpicxrefxrefxref
    part of humanized Fab GNC92H2
    complexed with coc
    1. region b:114-228 [61922] picpic