Structural Classification of Proteins

Fold: Immunoglobulin-like beta-sandwich

: sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: Immunoglobulin-like beta-sandwich [48725]
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands

Superfamilies:

Immunoglobulin [48726] (4)
E set domains [81296] (20)
"Early" Ig-like fold families possibly related to the immunoglobulin and/or fibronectin type III superfamilies
Fibronectin type III [49265] (1)
PKD domain [49299] (1)
beta-Galactosidase/glucuronidase domain [49303] (1)
Transglutaminase, two C-terminal domains [49309] (1)
Cadherin-like [49313] (2)
Actinoxanthin-like [49319] (1)
Cu,Zn superoxide dismutase-like [49329] (1)
has additional strand at N-terminus
CBD9-like [49344] (3)
has additional strand at N-terminus; the active site in a similar topological location as the Cu,Zn SOD site
Lamin A/C globular tail domain [74853] (1)
Clathrin adaptor appendage domain [49348] (3)
contains an additional N-terminal strand
Integrin domains [69179] (1)
PapD-like [49354] (2)
contains PP switch between strands D and C'
Purple acid phosphatase, N-terminal domain [49363] (1)
Fungal immunomodulatory protein, FIP [101542] (1)
Superoxide reductase-like [49367] (1)
Thiol:disulfide interchange protein DsbD, N-terminal domain (DsbD-alpha) [74863] (1)
Invasin/intimin cell-adhesion fragments [49373] (1)
Antigen MPT63/MPB63 (immunoprotective extracellular protein) [81982] (1)
Tp47 lipoprotein, middle and C-terminal domains [81986] (1)
ASF1-like [101546] (1)
contains extra C-terminal strand
ApaG-like [110069] (1)
Accessory protein X4 (ORF8, ORF7a) [117066] (1)
LEA14-like [117070] (1)
ICP-like [141066] (1)
topological variant with similarity to the Cupredoxin-like fold (scop_cf 49502) in the N-terminal region
CalX-like [141072] (1)