Structural Classification of Proteins
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Fold: Ribonuclease H-like motif

3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Ribonuclease H-like motif [53066]
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

Superfamilies:

  1. Actin-like ATPase domain [53067] (13)
    duplication contains two domains of this fold
    1. Actin/HSP70 [53068] (14) picpic
    2. BadF/BadG/BcrA/BcrD-like [64089] (5) picpic
    3. Acetokinase-like [53080] (3) picpic
    4. ATPase domain of dehydratase reactivase alpha subunit [82440] (2) picpic
    5. Hexokinase [53083] (5) picpic
    6. Glycerol kinase [53089] (2) picpic
    7. Glucokinase [110627] (1) picpic
      Pfam 02685
    8. Ppx/GppA phosphatase [110630] (2) picpic
      Pfam 02541
    9. YeaZ-like [110633] (2) picpic
      Pfam 00814; ubiquitous cytoplasmic protein; annotated as Glycoprotease (Peptidase_M22 family) on the basis of one member's known extracellular activity
    10. ROK [110636] (8) picpic
      Pfam 00480
    11. Cyto-EpsL domain [117644] (1) picpic
      N-terminal part of Pfam 05134
    12. Ta0583-like [142481] (1) picpic
    13. CoaX-like [142484] (3) picpic
      Pfam 03309; Bordetella pertussis Bvg accessory factor family, Baf
  2. Creatinase/prolidase N-terminal domain [53092] (1)
    1. Creatinase/prolidase N-terminal domain [53093] (4) picpic
  3. Ribonuclease H-like [53098] (12)
    consists of one domain of this fold
    1. Ribonuclease H [53099] (11) picpic
    2. Retroviral integrase, catalytic domain [53107] (3) picpic
    3. mu transposase, core domain [53112] (1) picpic
    4. Transposase inhibitor (Tn5 transposase) [53115] (1) picpic
    5. DnaQ-like 3'-5' exonuclease [53118] (24) picpic
      contains Pfam 00929
    6. RuvC resolvase [53134] (1) picpic
    7. Mitochondrial resolvase ydc2 catalytic domain [69533] (1) picpic
    8. Putative Holliday junction resolvase RuvX [102485] (3) picpic
    9. CAF1-like ribonuclease [102492] (1) picpic
    10. PIWI domain [110640] (3) picpic
      Pfam 02171
    11. TM1739-like [142505] (1) picpic
      Pfam 04251; DUF430; particular similarity to the PIWI domain family
    12. Hermes transposase-like [142508] (1) picpic
  4. Translational machinery components [53137] (2)
    1. Ribosomal protein L18 and S11 [53138] (4) picpic
    2. Middle domain of eukaryotic peptide chain release factor subunit 1, ERF1 [53143] (1) picpic
  5. Nitrogenase accessory factor-like [53146] (2)
    1. MTH1175-like [53147] (3) picpic
    2. Nitrogenase accessory factor [102496] (1) picpic
      capable of binding the iron molybdenum cofactor, FeMo-co
  6. DNA repair protein MutS, domain II [53150] (1)
    1. DNA repair protein MutS, domain II [53151] (2) picpic
  7. Methylated DNA-protein cysteine methyltransferase domain [53155] (1)
    1. Methylated DNA-protein cysteine methyltransferase domain [53156] (3) picpic
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MRC site Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007
Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk