Structural Classification of Proteins
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Fold: HIT-like

alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: HIT-like [54196]
    alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha

Superfamilies:

  1. HIT-like [54197] (3)
    1. HIT (HINT, histidine triad) family of protein kinase-interacting proteins [54198] (6) picpic
      Pfam 01230
      topologically similar to the N-terminal domain of protein kinases
    2. Hexose-1-phosphate uridylyltransferase [54207] (2) picpic
      duplication: consists of 2 HIT-like motifs
      binds zinc and iron ions
    3. mRNA decapping enzyme DcpS C-terminal domain [102745] (2) picpic
  2. Rotavirus NSP2 fragment, C-terminal domain [75347] (1)
    1. Rotavirus NSP2 fragment, C-terminal domain [75348] (1) picpic
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MRC site Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007
Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk