Structural Classification of Proteins




Protein: Cyclin-dependent PK, CDK2 from Human (Homo sapiens) [TaxId: 9606]
Lineage:
- Root: scop
- Class: Alpha and beta proteins (a+b) [53931]
Mainly antiparallel beta sheets (segregated alpha and beta regions)
- Fold: Protein kinase-like (PK-like) [56111]
consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
- Superfamily: Protein kinase-like (PK-like) [56112]
shares functional and structural similarities with the ATP-grasp fold and PIPK
- Family: Protein kinases, catalytic subunit [88854]
members organized in the groups and subfamiles specified by the comments
- Protein: Cyclin-dependent PK, CDK2 [88855]
CMGC group; CDKs subfamily; serine/threonine kinase
- Species: Human (Homo sapiens) [TaxId: 9606] [88856]
PDB Entry Domains:
- 1gz8

complexed with csw, mbp
- chain a [83405]


- 1h00

complexed with ace, fap, fcp
- chain a [83409]


- 1jvp

complexed with lig
- chain p [67371]


- 1urw

complexed with ace, i1p
- chain a [99836]


- 1oit

complexed with hdt
- chain a [93075]


- 1h0v

complexed with un4
- chain a [83443]


- 1hcl

- chain a [41593]


- 1h01

complexed with fal, fbl, gol, kcx
- chain a [83410]


- 1h08

complexed with ace, bwp, byp, gol
- chain a [83419]


- 1h07

complexed with ace, mfp, mfq
- chain a [83418]


- 1hck

complexed with atp, mg
- chain a [41594]


- 1oir

complexed with hdy
- chain a [93074]


- 1ke7

complexed with ls3
- chain a [72366]


- 1ke6

complexed with ls2
- chain a [72365]


- 1ke8

complexed with ls4
- chain a [72367]


- 1e1x

complexed with ace, nw1
- chain a [59157]


- 1e1v

complexed with ace, cmg
- chain a [59156]


- 1jsv

complexed with u55
- chain a [63278]


- 1b38

complexed with ace, atp, ium
- chain a [41595]


- 1ke9

complexed with ls5
- chain a [72368]


- 1pxi

complexed with ck1
- chain a [95289]


- 1gii

complexed with 1pu; mutant
- chain a [65218]


- 1pw2

- chain a [95197]


- 1ckp

complexed with edo, pvb
- chain a [41597]


- 1ke5

complexed with ls1
- chain a [72364]


- 1di8

complexed with dtq
- chain a [41601]


- 1pxo

complexed with ck7
- chain a [95295]


- 1aq1

complexed with stu
- chain a [41599]


- 1pye

complexed with pm1
- chain a [104390]


- 1r78

complexed with fmd
- chain a [97190]


- 1b39

complexed with ace, atp, ium
- chain a [41600]


- 1dm2

complexed with egl, hmd
- chain a [41598]


- 1h0w

complexed with 207
- chain a [83444]


- 1h1r


complexed with 6cp, tpo
- chain a [76489]


- chain c [76492]


- 1h1s


complexed with 4sp, tpo
- chain a [76495]


- chain c [76498]


- 1h1p


complexed with cmg, tpo
- chain a [76477]


- chain c [76480]


- 1h27


complex with cyclin and an 11-residue recruitment peptide from p27
complexed with tpo
- chain a [76534]


- chain c [76537]


- 1jsu



complexed with so4; mutant
- chain a [41603]


- 1fvt

complexed with 106
- chain a [41602]


- 1qmz


- chain a [41604]


- chain c [41605]


- 1p5e


complexed with tbs, tpo
- chain a [87796]


- chain c [87799]


- 1oi9


complexed with mg, n20, sgm
- chain a [103946]


- chain c [103949]


- 1h26


complex with cyclin and an 11-residue recruitment peptide from p53
complexed with tpo
- chain a [76528]


- chain c [76531]


- 1gij

complexed with 2pu; mutant
- chain a [65219]


- 1vyw


complexed with 292, so4
- chain a [108922]


- chain c [108925]


- 1okv


complex with cyclin
complexed with nh2
- chain a [93282]


- chain c [93285]


- 1pxj

complexed with ck2
- chain a [95290]


- 1fin


complexed with atp
- chain a [41606]


- chain c [41607]


- 1pkd


complexed with tpo, ucn
- chain a [88141]


- chain c [88144]


- 1vyz

complexed with n5b
- chain a [108928]


- 1okw


complex with cyclin
complexed with ace, fcl, nh2
- chain a [93288]


- chain c [93291]


- 1v1k

complexed with 3fp, ace
- chain a [100255]


- 1pxp

complexed with ck8
- chain a [95296]


- 1oiq

complexed with hdu
- chain a [93073]


- 1p2a

complexed with 5bn
- chain a [87719]


- 1pxl

complexed with ck4
- chain a [95292]


- 1pf8

complexed with su9
- chain a [94605]


- 1buh


- chain a [41608]


- 1ol2


complex with cyclin
complexed with nh2, pff
- chain a [93304]


- chain c [93307]


- 1gih

complexed with 1pu
- chain a [65217]


- 1urc


complexed with ace
- chain a [113404]


- chain c [113407]


- 1ogu


complex with cyclin
complexed with sgm, st8
- chain a [92942]


- chain c [92945]


- 1g5s

complexed with i17
- chain a [65167]


- 1jst


complexed with atp, mn
- chain a [41609]


- chain c [41610]


- 1h24


complex with cyclin and a 9 residue recruitment peptide from E2F
complexed with tpo
- chain a [76516]


- chain c [76519]


- 1oiu


complexed with mg, n76, sgm
- chain a [103958]


- chain c [103961]


- 1e9h


complexed with inr
- chain a [64812]


- chain c [64815]


- 1pxn

complexed with ck6
- chain a [95294]


- 1pxm

complexed with ck5
- chain a [95293]


- 1f5q


complexed with cl
- chain a [41611]


- chain c [41612]


- 1oiy


complexed with mg, n41, sgm
- chain a [103964]


- chain c [103967]


- 1h25


complex with cyclin and an 11-residue recruitment peptide from retinoblastoma-associated protein
complexed with tpo
- chain a [76522]


- chain c [76525]


- 1pxk

complexed with ck3
- chain a [95291]


- 1h1q


complexed with 2a6, tpo
- chain a [76483]


- chain c [76486]


- 2cch





automatically matched to d1vywa_
complexed with atp, gol, so4
- region a:1-296 [130236]


- 2cch





automatically matched to d1vywa_
complexed with atp, gol, so4
- region c:1-296 [130239]


- 2clx

automatically matched to d1vywa_
complexed with f18
- region a:1-298 [130600]


- 2fvd

automatically matched to d1vywa_
complexed with lia
- region a:1-298 [134200]


- 2exm

automatically matched to d1vywa_
complexed with zip
- region a:1-298 [132561]


- 2b54

automatically matched to d1vywa_
complexed with d05
- region a:1-298 [127876]


- 2c6i

automatically matched to d1vywa_
complexed with dt1
- region a:1-298 [129995]


- 2c6k

automatically matched to d1vywa_
complexed with dt2
- region a:1-298 [129997]


- 2c68

automatically matched to d1vywa_
complexed with ct6
- region a:1-297 [129985]


- 2b55

automatically matched to d1vywa_
complexed with d31
- region a:1-298 [127877]


- 2c6m

automatically matched to d1vywa_
complexed with dt5
- region a:1-297 [129999]


- 2a0c

automatically matched to d1vywa_
complexed with ck9
- region x:1-298 [125945]


- 2b52

automatically matched to d1vywa_
complexed with d42
- region a:1-298 [127874]


- 2btr

automatically matched to d1vywa_
complexed with u73
- region a:1-298 [129157]


- 1y8y

automatically matched to d1vywa_
complexed with ct7
- region a:1-298 [122770]


- 1w8c

automatically matched to d1vywa_
complexed with ace, n69
- region a:1-298 [120718]


- 1ykr

automatically matched to d1vywa_
complexed with 628
- region a:1-298 [123560]


- 2c5n





automatically matched to d1vywa_
complexed with ck8
- region a:1-296 [129926]


- 2c5n





automatically matched to d1vywa_
complexed with ck8
- region c:1-297 [129929]


- 1w98

automatically matched to d1vywa_
- region a:1-297 [120776]


- 2bts

automatically matched to d1vywa_
complexed with u32
- region a:1-298 [129158]


- 2uue





automatically matched to d1vywa_
complexed with gvc, mtz, nh2, pff
- region a:1-296 [139972]


- 2uue





automatically matched to d1vywa_
complexed with gvc, mtz, nh2, pff
- region c:1-297 [139975]


- 2ds1

automatically matched to d1giia_
complexed with 1cd; mutant
- region a:1-298 [131680]


- 1wcc

automatically matched to d1vywa_
complexed with cig
- region a:1-298 [120886]


- 2b53

automatically matched to d1vywa_
complexed with d23
- region a:1-298 [127875]


- 2bhe

automatically matched to d1vywa_
complexed with bry
- region a:1-298 [128526]

