Structural Classification of Proteins

Superfamily: Cysteine proteinases

: the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Lineage:

Root: scop
Class: Alpha and beta proteins (a+b) [53931]
Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold: Cysteine proteinases [54000]
consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
Superfamily: Cysteine proteinases [54001]
the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Papain-like [54002] (30)
Avirulence protein Avrpph3 [102723] (1)
FMDV leader protease [54037] (1)
Calpain large subunit, catalytic domain (domain II) [54040] (5)
Transglutaminase core [54044] (5)
Arylamine N-acetyltransferase [54047] (4)
fold similar to that of the factor XIII catalytic domain
Ubiquitin carboxyl-terminal hydrolase UCH-L [54050] (3)
Ubiquitin carboxyl-terminal hydrolase, UCH [82568] (4)
Pfam 00443
Adenain-like [54054] (5)
Pfam 02902; Ulp1 protease family
Microbial transglutaminase [75336] (1)
inverted positions of the catalytic triad Asp and His residues
Ubiquitin thiolesterase protein OTUB2 (Otubain-2) [110773] (1)
probably the same as Pfam 02338, OTU-like cysteine protease, but 1TFF (SQ Q96DC9) was not detected by the Pfam model
IgG-specific endopeptidase IdeS (Sib38) [117762] (1)
Lpg0564-like [142864] (1)
Pfam 07313, DUF1460; contains new PDB entry 2p1g, annotated as putative xylanase
Phytochelatin synthase [142867] (1)
Pfam 05023; assosiated Pfam 09328 (DUF1984) is a part of the same functional unit
CHAP domain [142870] (1)
Pfam 05257
NlpC/P60 [142873] (1)
Pfam 00877