Class: Alpha and beta proteins (a+b)

Mainly antiparallel beta sheets (segregated alpha and beta regions)

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)

Folds:

1. Microbial ribonucleases [53932] (1)
   single helix packs against antiparallel beta-sheet
2. Lysozyme-like [53954] (1)
   common alpha+beta motif for the active site region
3. Cysteine proteinases [54000] (1)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
4. His-Me finger endonucleases [54059] (1)
   core: (alpha)-beta-omega_loop-beta-alpha; embeded in larger different structures
5. RNase A-like [54075] (1)
   contains long curved beta-sheet and 3 helices
6. EndoU-like [142876] (1)
   comprises several helices and two three-stranded antiparallel beta-sheets; similar architecture to the RNase A-like fold (scop_cf 54075)
7. Prion-like [54097] (1)
   beta-alpha-beta-alpha(2); antiparallel beta-ribbon
8. LysM domain [54105] (1)
   beta-alpha(2)-beta; antiparallel strands
9. Head-to-tail joining protein W, gpW [64209] (1)
   alpha-beta(2)-alpha; antiparallel hairpin
10. Hypothetical protein MTH677 [110782] (1)
    alpha-beta(2)-alpha; 2 layers a/b; antiparallel beta-hairpin
11. GTF2I-like repeat [117772] (1)
    alpha(2)-beta-alpha-beta-alpha; 2 layers: a/b; antiparallel beta-ribbon
12. Urease, gamma-subunit [54110] (1)
    alpha(3)-beta(2); antiparallel hairpin
13. IL8-like [54116] (2)
    beta(3)-alpha
14. DNA-binding domain [54170] (1)
    beta(3)-alpha; 2 layers: alpha/beta
15. Penicillin-binding protein 2x (pbp-2x), c-terminal domain [54183] (1)
    alpha1-beta3; 2 layers: alpha/beta; order 132
16. Dodecin subunit-like [88797] (5)
    beta-alpha-beta(2); 2 layers: alpha/beta; antiparallel beta-sheet: order 132
17. Ribosomal proteins S24e, L23 and L15e [54188] (1)
    beta-(alpha)-beta-alpha-beta(2); 3 layers: alpha/beta/alpha; antiparallel beta-sheet: order 1243
18. Ribosome binding domain-like [100965] (2)
    beta-(2)-alpha(2)-beta(2); 2 layers: beta/alpha; antiparallel beta-sheet: order 1243; topological similarity to the common core of ribosomal proteins L23 and L15e
19. TFB5-like [142896] (1)
    beta-alpha-beta(2)-alpha; 2 layers, a/b; antiparallel sheet, order: 132; dimerises in solution (PDB 2jnj) via extended N-terminal strand
20. Obg GTP-binding protein C-terminal domain [102740] (1)
    beta-(2)-alpha(3)-beta(2); 2 layers: beta/alpha; mixed beta-sheet: order 1234; strands 2 and 3 a parallel to each other
21. HIT-like [54196] (2)
    alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha
22. Secretion chaperone-like [69634] (3)
    alpha-beta(3)-alpha-beta(2)-alpha; 2 layers: alpha/beta
23. DNA-binding domain of intron-encoded endonucleases [64495] (1)
    beta(2)-alpha(2)-beta; 2 layers; 3-stranded antiparallel beta-sheet, order 213; HTH motif; also includes the extra N-terminal, DNA minor groove-binding helix
24. MotA C-terminal domain-like [69651] (1)
    alpha-beta(4)-alpha-beta(2)-alpha; 2 layers: alpha/beta
25. YktB/PF0168-like [142912] (1)
    alpha-beta(4)-alpha-beta(2)-alpha-beta-alpha; 2 layers, a/b; antiparallel beta-sheet, order: 1234756; half-barrel shape; topological similarity to the MotA C-terminal domain-like fold (scop_cf 69651) and the Secretion chaperone-like fold (scop_cf 69634)
26. Mago nashi protein [89816] (1)
    beta(4)-alpha-beta(2)-alpha; 2 layers: alpha/beta; antiparallel beta-sheet, order: 651234
27. WGR domain-like [142920] (1)
    beta(4)-alpha-X-beta; 2 layers, a/b; antiparallel beta-sheet, order 51234; the beta-hairpin insetrion in strand 1 results in the formation of a beta-triangle structure
28. Ribosomal protein S5 domain 2-like [54210] (1)
    core: beta(3)-alpha-beta-alpha; 2 layers: alpha/beta; left-handed crossover
29. beta-Grasp (ubiquitin-like) [54235] (13)
    core: beta(2)-alpha-beta(2); mixed beta-sheet 2143
30. WWE domain [117838] (1)
    beta(2)-alpha-beta(4); antiparallel folded beta-sheet (half-barrel), order 216543
31. FAD-linked reductases, C-terminal domain [54372] (1)
    alpha+beta sandwich
32. Cystatin-like [54402] (7)
    Core: alpha-beta(4); helix packs against coiled antiparallel beta-sheet
33. Nuclease A inhibitor (NuiA) [82601] (1)
    alpha-beta-alpha-beta-alpha(2)-beta(3); antiparallel beta-sheet; order: 15432
34. Colicin D/E5 nuclease domain [102823] (1)
    alpha(2)-beta(4)-alpha, 2 layers: alpha/beta, antiparallel beta sheet, meander
35. RelE-like [143010] (1)
    beta-alpha(2)-beta(4), 2 layers; a/b, antiparallel beta-sheet; order 15432
36. Hypothetical protein SAV1430 [110835] (1)
    beta(3)-alpha-beta(2)-alpha; 2 layers, alpha/beta; antiparallel beta-sheet, order: 12543
37. Ns1 effector domain-like [143020] (1)
    beta-X-beta(5)-alpha-beta-alpha; 2 layers: a/b; bifurcated beta-sheet; order 23654[1,7]
38. YbaB-like [82606] (1)
    core: alpha-beta(3)-alpha, 2 layers:alpha/beta, three-stranded antiparallel beta sheet, strand order 123
39. Kinetochore globular domain-like [143025] (1)
    core: alpha-beta(3)-alpha; variant: alpha-beta(4)-alpha(2)
40. L35p-like [143033] (1)
    core: alpha-beta(3)-alpha; 2layers a/b
41. Cell division protein ZapA-like [102828] (1)
    core: beta(2)-alpha(2), 2 layers: alpha/beta; long C-terminal helix forms dimeric parallel and tetrameric antiparallel coiled coils
42. ssDNA-binding transcriptional regulator domain [54446] (1)
    helix-swapped dimer of beta(4)-alpha motifs
43. Photosystem I subunit PsaD [64233] (1)
    beta-BETA(2)-beta-alpha-beta(2); antiparallel sheet: order 2134 packed against helix and BETA-hairpin on the same side; irregular C-terminal tail
44. MHC antigen-recognition domain [54451] (1)
    dimeric
45. UBC-like [54494] (1)
    alpha-beta(4)-alpha(3); core: meander beta-sheet plus one helix 2
46. SAND domain-like [63762] (1)
    core: three short helices packed against a barrel-like beta-sheet; some similarity to the SH3-like fold
47. Coronavirus NSP8-like [143075] (1)
    core: alpha-beta(2)-alpha-beta(4)-alpha-beta; bifurcated barrel-like beta-sheet
48. ParB/Sulfiredoxin [110848] (1)
    beta*-alpha-beta(2)-alpha-beta-alpha; mixed beta sheet forms a partly open barrel: (n*=4, S*=8)
49. BtrG-like [110856] (1)
    beta-alpha-beta(4)-alpha-beta(2); contains beta-sheet barrel (n=5, S=8)
50. BB1717-like [143080] (1)
    complex fold with a bifurcated beta-sheet structure surrounded by helices; contains beta-sheet barrel, closed (n=5, S=8)
51. AF0104/ALDC/Ptd012-like [117855] (1)
    duplication: consists of two similar beta-alpha-beta(4) motifs
52. NSFL1 (p97 ATPase) cofactor p47, SEP domain [102847] (1)
    beta(3)-alpha(2)-beta; 2 layers; mixed beta-sheet, order 4123, strands 1 and 4 are parallel to each other
53. TTHA1013-like [143099] (1)
    beta(3)-alpha-beta; 2 layers; mixed beta-sheet, order 4123, strands 1 and 4 are parallel to each other; topological similarity to the SEP domain fold (scop_cf 102847); dimerises via the long C-terminal strand with the formation of a single beta-sheet
54. Diaminopimelate epimerase-like [54505] (1)
    mixed beta-sheet folds into a barrel (n=8, S=14) around the central helix
55. GFP-like [54510] (1)
    beta-sheet folds into a barrel (n=11, S=14) around the central helix
56. Tubby C-terminal domain-like [54517] (1)
    beta-sheet folds into a barrel (n=12, S=12) around the central helix
57. Pili subunits [54522] (1)
    contains very long N-terminal helix, which end is packed against beta-sheet
58. Mitochondrial glycoprotein MAM33-like [54528] (1)
    core: beta(7)-alpha(2); N- and C-terminal extensions form a coiled coil subdomain
59. NAP-like [143112] (1)
    core: central meander 4-stranded beta-sheet (order: 1234) transversed by a C-terminal helix
60. Polo-box domain [82614] (1)
    beta(6)-alpha; antiparallel beta-sheet, meander
61. mRNA decapping enzyme DcpS N-terminal domain [102859] (1)
    beta(3)-alpha-beta(3)-alpha; 3 layers a/b/a
62. Inhibitor of vertebrate lysozyme, Ivy [89871] (1)
    alpha(2)-beta(5)-alpha(2); 3 layers a/b/a; meander beta-sheet
63. FKBP-like [54533] (3)
    core: beta(2)-alpha-beta(2); antiparallel beta-sheet
64. Ribosomal protein S16 [54564] (1)
    beta(4)-alpha-beta; 2 layers: alpha/beta; mixed beta-sheet, order: 51234
65. Ribosomal protein S19 [54569] (1)
    alpha-beta-X-beta(2); 2 layers: alpha/beta; mixed beta-sheet, order: 123
66. YefM-like [143119] (1)
    core: beta-alpha(2)-beta(2)-alpha; mixed beta-sheet, order:123, strands 1 and 2 are parallel; forms compact dimer with a single beta-sheet;
67. Ribosomal protein L31e [54574] (1)
    beta-alpha-beta-(alpha)-beta(2); 2 layers: alpha/beta; mixed beta-sheet, order: 1342
68. Allophycocyanin linker chain (domain) [54579] (1)
    beta(2)-alpha-beta; 2 layers: alpha/beta
69. Cdc48 domain 2-like [54584] (1)
    beta-alpha-beta(3); 2 layers: alpha/beta
70. Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [54592] (1)
    beta-alpha-beta(3); 2 layers: alpha/beta
71. Chromosomal protein MC1 [102874] (1)
    beta(2)-alpha-beta(3); 2 layers: alpha/beta
72. beta-hairpin-alpha-hairpin repeat [74651] (2)
    multiple repeats of beta(2)-alpha(2) motif
73. Proguanylin [89889] (1)
    beta(2)-alpha(3)-beta; two layers: alpha/beta; antiparallel sheet: order 213
74. Bacterial protein-export protein SecB [54610] (1)
    beta(4)-alpha(2); two layers: alpha/beta; antiparallel sheet: order 1432
75. MesJ substrate recognition domain-like [82828] (1)
    beta-alpha(2)-beta(3); 2 layers: a/b; antiparallel beta-sheet, order:1432
76. FYSH domain [89894] (1)
    beta(2)-alpha(2)-beta(2)-alpha-beta; two layers: alpha/beta; antiparallel sheet: order 51234
77. VSV matrix protein [75403] (1)
    beta-alpha(2)-beta(4)-alpha-beta(2); two layers: alpha/beta; bifurcated coiled beta-sheet: order of the first 5 strands: 23154
78. DNA-binding domain of Mlu1-box binding protein MBP1 [54615] (1)
    beta(4)-alpha(2)-beta(2)-alpha; antiparallel sheet: order 123465
79. Heme-binding protein A (HasA) [54620] (1)
    beta-alpha-beta(6)-alpha(2); antiparallel sheet: order 165432
80. Chalcone isomerase [54625] (1)
    beta(3)-alpha(2)-beta-alpha(2)-beta3; 2 layers alpha/beta; antiparallel sheet: order 1234567
81. Coproporphyrinogen III oxidase [102885] (1)
    alpha-beta(6)-alpha(2)-beta-alpha(n); 3 layers alpha/beta/alpha; antiparallel sheet: order 1234567
82. Hypothetical protein Ta1206 [102890] (1)
    beta(4)-alpha-beta(2)-alpha(2); mixed, predominately antiparallel beta-sheet, order: 123465, strands 4 and 5 are parallel to each other
83. CBS-domain [54630] (1)
    core: beta-alpha-beta(4); 2 layers: alpha/beta
84. Thioesterase/thiol ester dehydrase-isomerase [54636] (1)
    core: beta-alpha-beta(4); 2 layers: alpha/beta
85. DLC [54647] (1)
    core: beta-alpha(2)-beta-X-beta(2); 2 layers: alpha/beta; antiparallel beta-sheet: order 1342
86. CI-2 family of serine protease inhibitors [54653] (1)
    alpha+beta sandwich; loop across free side of beta-sheet
87. Integrin beta tail domain [69686] (1)
    alpha-beta-loop-beta(3); loop across free side of beta-sheet
88. alpha/beta-Hammerhead [54664] (5)
    core: beta-BETA-alpha-beta-BETA-beta-alpha; contains a beta-hammerhead motif similar to that in barrel-sandwich hybrids
89. POZ domain [54694] (1)
    core: beta(2)-alpha(2)-beta(2)-alpha(2); 2 layers a/b; mixed sheet: 2143
90. EF-Ts domain-like [54712] (2)
    beta(2)-alpha(n)-beta; 2 layers a/b; antiparallel sheet: 123
91. Fe,Mn superoxide dismutase (SOD), C-terminal domain [54718] (1)
    alpha-beta(2)-alpha-beta-alpha(2); 3 strands of antiparallel sheet: 213
92. ClpS-like [54735] (1)
    beta-alpha(2)-beta-alpha-beta; 2 layers, alpha/beta
93. Hypothetical protein MTH1880 [75411] (1)
    beta-alpha-beta(2)-alpha(2); 3 layers, alpha/beta/alpha; antiparallel beta-sheet: order 123
94. Ribosomal L11/L12e N-terminal domain [54746] (1)
    beta-alpha(2)-beta(2); 2 layers, alpha/beta; antiparallel beta-sheet: order 123
95. Anti-LPS factor/recA domain [54751] (2)
    alpha-beta(3)-alpha(2); 2 layers, alpha/beta
96. Signal recognition particle alu RNA binding heterodimer, SRP9/14 [54761] (1)
    (beta)-alpha-beta(3)-alpha; 2 layers, alpha/beta
97. dsRBD-like [54767] (5)
    alpha-beta(3)-alpha; 2 layers: alpha/beta
98. 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain [110920] (1)
    duplication: consists of two beta(3)-alpha repeats; 3 layers, beta/alpha/beta
99. SRP19 [69694] (1)
    beta-alpha-beta(2)-alpha; 2 layers: alpha/beta
100. SufE/NifU [82648] (1)
     alpha(2)-beta(3)-alpha(3); 2 layers alpha/beta, 3-stranded antiparallel beta-sheet; order 123
101. DNA-binding protein Tfx [89914] (1)
     alpha(3)-beta-alpha(2)-beta(2); 2 layers alpha/beta, 3-stranded antiparallel beta-sheet; order 123
102. Eukaryotic type KH-domain (KH-domain type I) [54790] (1)
     beta-alpha(2)-beta(2)-alpha; 2 layers: alpha/beta
103. Alpha-lytic protease prodomain-like [54805] (8)
     core: alpha-beta(2)-(alpha)-beta; 2 layers: alpha/beta
104. Nucleotidyltransferase [81302] (1)
     core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123
105. Nqo5-like [143242] (1)
     core: alpha-beta(2)-alpha-beta(3); 2 layers, a/b; mixed beta-sheet, order 12534, strands 2 and 5 are parallel
106. Ribosomal protein S3 C-terminal domain [54820] (1)
     alpha(2)-beta(4); 2 layers: alpha/beta; antiparallel beta-sheet: order 2143
107. Transcription factor NusA, N-terminal domain [69704] (1)
     alpha-beta(3)-alpha-beta-alpha; bifurcated coiled beta-sheet
108. Enolase N-terminal domain-like [54825] (1)
     beta(3)-alpha(3); meander and up-and-down bundle
109. Ribosomal protein L22 [54842] (1)
     beta-alpha(3)-beta(2); 2 layers: alpha/beta; related to the enolase/MLE N-domain fold by a circular permutation
110. Prokaryotic ribosomal protein L17 [64262] (1)
     alpha-beta-alpha(3)-beta(2); 2 layers: alpha/beta;
111. GroEL-intermediate domain like [54848] (1)
     3-helical bundle packed against 3-stranded mixed beta-sheet
112. PX domain [64267] (1)
     beta(3)-alpha(4); meander beta-sheet packed against array of helices; contains Pro-rich stretch
113. DsrC, the gamma subunit of dissimilatory sulfite reductase [69720] (1)
     beta(3)-alpha(5); meander beta-sheet packed against array of helices
114. DNA damage-inducible protein DinI [54856] (1)
     beta-alpha-beta(2)-alpha; 2 layers: alpha/beta; mixed sheet 213; crossing loops
115. HSP90 C-terminal domain [110941] (1)
     alpha-beta(3)-alpha(3); 2 layers, a/b; mixed beta-sheet, order:132; crossing loops
116. Ferredoxin-like [54861] (55)
     alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
117. PurS-like [109622] (1)
     consists of two alpha+beta subdomains with some similarity to the ferredoxin-like fold
118. Dystroglycan, domain 2 [111005] (1)
     beta-alpha-beta-X-beta(2)-alpha(2)-beta; antiparallel beta-sheet, order 24153; topological similarity to the ferredoxin-like fold (scop_cf 54861)
119. Pseudouridine synthase [100877] (1)
     consists of two alpha+beta subdomains with some similarity to the ferredoxin-like fold
120. Folate-binding domain [103024] (1)
     duplication: consists of two beta(2)-alpha-beta(3)-alpha subdomains swapped with the first strands
121. THUMP domain [143436] (1)
     contains mixed 8-stranded beta-sheet, folded into a half-barrel and covered with 4 helices on the outside; order 32148756; strands 5, 6 and 7 are parallel
122. AMMECR1-like [143446] (1)
     duplication; contains two beta(2)-alpha-beta(2) structural repeats, swapped with C-terminal strands; extra N-terminal helix and C-terminal strand
123. YehU-like [118000] (1)
     beta-alpha(2)-beta(2)-alpha; 3 layers, alpha/beta/alpha; antiparallel beta-sheet: order 123
124. Hypothetical protein YwqG [103031] (1)
     duplication: contains two similar beta-x-beta(4) motifs swapped with the first strands
125. VC0467-like [143455] (1)
     complex fold; contains bifurcated beta-sheet structure folded into pseudo barrel
126. Lesion bypass DNA polymerase (Y-family), little finger domain [100878] (1)
     beta-alpha-beta(2)-alpha-beta; antiparallel beta-sheet: order 1423; "reversed" ferredoxin-like topology
127. ImmE5-like [143468] (1)
     alpha-beta(2)-alpha-beta; 2 layers, a/b; antiparallel beta-sheet, order 213
128. Ribosomal protein L30p/L7e [55128] (1)
     core: beta-alpha-beta-alpha-beta; antiparallel beta-sheet: order 312; some similarity to the ferredoxin-like fold
129. Chorismate lyase-like [64287] (1)
     duplication of alpha(2)-beta(3) motif; antiparallel beta sheet, order 123654
130. TM1622-like [143476] (1)
     alpha-beta(3)-alpha-beta(4)-alpha; 3 layers, a/b/a; antiparallel beta-sheet, order: 1237654
131. Probable bacterial effector-binding domain [55135] (1)
     duplication of beta-alpha-beta(2) motif: antiparallel beta sheet forms barrel (n=6, S=12)
132. CheC-like [103038] (1)
     duplication: tandem repeat of two intertwined alpha-beta-(X)-beta(2) motifs
133. LigT-like [55143] (1)
     duplication of beta-alpha-beta-alpha-beta motif: antiparallel beta sheet forms barrel (n=6, S=8) similar to the barrel of prokaryotic DNA topoisomerases I and III
134. Pepsin inhibitor-3 [55148] (1)
     duplication of beta(3)-alpha(2) motif: meander beta sheets form barrel-like structure
135. CYTH-like phosphatases [55153] (1)
     duplication of beta-alpha-beta(3) motif: antiparallel beta sheet forms wide barrel (n=8, S=16) with a channel running through it
136. Antiparallel beta/alpha barrel (PT-barrel) [143491] (1)
     tandem repeat of five alpha(2)-beta(2) motifs; antiparallel beta-sheet barrel, closed; n=10, S=10; order 123456789A; there is a channel along the barrel axis
137. eIF1-like [55158] (2)
     beta(2)-alpha-beta(2)-alpha-beta; 2 layers: alpha/beta; mixed beta-sheet: order 51243
138. Hedgehog/DD-peptidase [55165] (1)
     alpha-beta(2)-alpha-beta(2); 2 layers: alpha/beta
139. Alpha-L RNA-binding motif [55173] (1)
     alpha(2)-beta(2)-loop-beta; 2 layers: alpha/beta
140. RRF/tRNA synthetase additional domain-like [55185] (4)
     core: alpha-beta(2)-alpha-beta(2); 2 layers: alpha/beta
141. LuxS/MPP-like metallohydrolase [63410] (1)
     core: beta-alpha-beta(2)-alpha(2); 2 layers: alpha/beta
142. IF3-like [55199] (7)
     beta-alpha-beta-alpha-beta(2); 2 layers; mixed sheet 1243, strand 4 is antiparallel to the rest
143. PUG domain-like [143502] (1)
     alpha(2)-beta-alpha(2)-beta(2)-alpha; cluster of helices with a small antiparallel beta-sheet on one side; order 132; topological similarity to the fold of an extended R3H domain (PDB 1whr)
144. Ribosome binding protein Y (YfiA homologue) [69753] (1)
     beta-alpha-beta(3)-alpha; 2 layers; mixed sheet 1234, strand 3 is antiparallel to the rest
145. TolA/TonB C-terminal domain [74652] (1)
     beta(2)-alpha-beta; 2 layers, alpha/beta; left-handed beta-alpha-beta unit in non-swapped monomer
146. Yeast killer toxins [55220] (1)
     beta-alpha-beta(2)-alpha-beta(2); 2 layers, alpha/beta; left-handed crossover connection
147. Cell division protein MinE topological specificity domain [55228] (1)
     dimer of alpha-beta(2) motifs ; 2 layers, alpha/beta
148. Hypothetical protein YoaG [103062] (1)
     dimer of beta(2)-alpha motifs ; 2 layers, alpha/beta; reverse MinE topology
149. Nucleocapsid protein dimerization domain [103067] (1)
     dimer of alpha-beta(2)-alpha motifs ; 2 layers, alpha/beta
150. Cyanase C-terminal domain [55233] (1)
     intertwined dimer of alpha-beta(2) motifs ; 2 layers, alpha/beta
151. Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains [82713] (1)
     Intertwined pseudo hexamer of an alpha+beta motif
152. RuBisCO, small subunit [55238] (1)
     alpha-beta(2)-alpha-beta(2); 2 layers, alpha/beta
153. DCoH-like [55247] (4)
     beta(2)-alpha-beta(2)-alpha; 2 layers, alpha/beta
154. TRCF domain-like [143516] (1)
     beta-alpha(3)-beta(2)-alpha-beta(2)-alpha; 2 layers: alpha/beta; mixed beta sheet, order 12354, strands 1 and 2 are parallel; some topological similarity to the DCoH-like fold (scop_cf 55247)
155. Hypothetical protein Yml108w [100886] (1)
     beta(2)-alpha-beta(2)-alpha; 2 layers, alpha/beta; mixed beta-sheet 2143, strands 1 and 4 are parallel
156. MutS N-terminal domain-like [55266] (2)
     beta(2)-alpha-beta(2)-alpha-beta(2); 2 layers, alpha/beta
157. GYF domain [55276] (1)
     beta(2)-alpha-beta(2)-alpha; 2 layers, alpha/beta
158. GTP cyclohydrolase I feedback regulatory protein, GFRP [69760] (1)
     beta(2)-alpha-beta(2)-alpha-beta(2); 2 layers, alpha/beta, antiparallel beta-sheet: order 342165
159. Ribosomal protein L5 [55281] (1)
     beta-alpha-beta(2)-alpha-beta(3)-alpha; 2 layers, alpha/beta; antiparallel beta-sheet: order 231654
160. RPB5-like RNA polymerase subunit [55286] (1)
     core: beta-alpha-beta-alpha-beta(2); 2 layers, alpha/beta
161. Bacillus chorismate mutase-like [55297] (7)
     core: beta-alpha-beta-alpha-beta(2); mixed beta-sheet: order: 1423, strand 4 is antiparallel to the rest
162. YjbQ-like [111037] (1)
     beta(2)-alpha-beta(2)-alpha(2)-beta(3); contains a beta-sandwich: 7 strands in 2 sheets; trimerizes with orthogonally packed beta-sheets
163. Tautomerase/MIF [55330] (1)
     (beta-alpha-beta)2; 2 layers: alpha/beta; mixed beta-sheet
     generally forms trimers with three closely packed beta-sheets
164. FwdE/GAPDH domain-like [55346] (3)
     core: alpha-beta-alpha-beta(3); mixed sheet: 2134, strand 2 is parallel to strand 1
165. Hypothetical protein PF0899 [111056] (1)
     alpha-beta-alpha-beta(4); 2 layers: a/b; mixed beta-sheet, order 23145, strands 1 and 3 are parallel; similar to the GAPDH C-terminal domain-like fold (scop_cf 55346)
166. Major capsid protein gp5 [56562] (1)
     unusual fold; contains PF0899-like core, decorated with additional structure
167. MK0786-like [143559] (1)
     alpha(2)-beta(4); 2 layers: a/b; antiparallel beta-sheet, order 1234 (meander)
168. YkuJ-like [143566] (1)
     alpha-beta(4)-alpha; 2 layers a/b; antiparallel beta-sheet, order 1234
169. N domain of copper amine oxidase-like [55382] (5)
     alpha-beta(5)-alpha; 2 layers: alpha/beta; meander antiparallel sheet
170. Aha1/BPI domain-like [55393] (2)
     core: [beta]-alpha-beta(5)-alpha; 2 layers: alpha/beta; antiparallel beta-sheet, meander
171. Subtilisin inhibitor [55398] (1)
     alpha+beta sandwich
172. RNA bacteriophage capsid protein [55404] (1)
     6-standed beta-sheet followed with 2 helices; meander
173. eIF4e-like [55417] (1)
     beta(2)-alpha-beta(2)-alpha-beta(2)-alpha-beta-2; 2 layers: alpha/beta; antiparallel sheet: 21356478
174. CO dehydrogenase flavoprotein C-domain-like [55423] (2)
     core: beta(3,4)-alpha(3); alpha+beta sandwich
175. SRF-like [55454] (1)
     alpha-beta(2)-alpha; dimer; 3 layers a/b/a; antiparallel beta-sheet
176. Origin of replication-binding domain, RBD-like [55463] (1)
     alpha-beta-alpha-beta(2)-alpha-beta-alpha-beta; 3 layers: a/b/a; antiparallel sheet 41325
177. SARS receptor-binding domain-like [143586] (1)
     core: 3 layers, a/b/a; antiparallel beta-sheet of 5 strands, order 13542
178. Hut operon positive regulatory protein HutP [111063] (1)
     alpha(2)-beta-alpha(2)-beta(3); 3 layers: a/b/a; antiparallel beta-sheet: order 1234
179. Hypothetical protein yfbM [111068] (1)
     beta-alpha(2)-beta-alpha(2)-beta(2)-alpha(n)-beta; 3 layers: a/b/a; antiparallel beta-sheet, order: 21543
180. TTHA1528-like [143591] (1)
     beta-alpha-beta(3)-alpha-beta-alpha(2)-beta; 3 layers: a/b/a; mixed beta-sheet, order: 143256, parallel strands' pairs are 1-4 and 2-5
181. YojJ-like [143596] (1)
     alpha-beta-X-beta-alpha-beta(2)-alpha-beta(3); 3 layers: a/b/a; 7-stranded mixed beta-sheet, order 2431567; strands 1 and 3 are parallel to each other
182. STIV B116-like [143601] (1)
     subunit fold consists of mixed 5-stranded beta-sheet, order:31452, strand 5 is antiparallel to the rest, with 3 helices on one side; dimerises with the formation of a single 10-stranded beta-sheet; strand 2 is in the dimer interface
183. Bacillus phage protein [111073] (1)
     alpa-beta(3)-alpha-beta(3)-alpha; 3 layers: b/a/b, 3-helical bundle flanked by two 3-stranded meander beta-sheets
184. FMN-dependent nitroreductase-like [55468] (1)
     core: (alpha-beta-alpha-beta)2; 3 layers a/b/a; antiparallel beta-sheet: 1243
185. N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 [55480] (1)
     alpha-beta-alpha(2)-beta(3)-alpha; 3 layers a/b/a; antiparallel beta-sheet: 4123
186. Zincin-like [55485] (2)
     contains mixed beta sheet with connection over free side of the sheet
187. SH2-like [55549] (1)
     3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
188. HPr-like [55593] (2)
     beta-alpha-beta(2)-alpha-beta-alpha; 2 layers: a/b; antiparallel sheet 1423
189. TrkA C-terminal domain-like [116725] (1)
     beta-X-beta(2)-X-beta-alpha; pseudo barrel capped by helix at one end; topological similarity to the HPr-like fold
190. Hypothetical protein YjiA, C-terminal domain [90001] (1)
     beta-alpha-beta(4)-alpha; 2 layers: a/b; antiparallel sheet 15234; topological similarity to the HPr-like fold
191. YggU-like [69785] (1)
     beta(2)-loop-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243; some similarity to the Homing endonuclease-like fold
192. Homing endonuclease-like [55603] (2)
     alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243
193. T-fold [55619] (2)
     beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
     tunnel-shaped: its known members form wide oligomeric barrels different sizes
194. Cell cycle regulatory proteins [55636] (1)
     beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1243
     can form strand-exchange dimers
195. beta-lactamase-inhibitor protein, BLIP [55647] (1)
     alpha(2)-beta(4); 2 layers: alpha/beta
196. Ribosomal protein L9 C-domain [55652] (1)
     alpha-beta-alpha(2)-beta(2); 2 layers: alpha/beta
197. L9 N-domain-like [55657] (1)
     beta(2)-alpha-beta-alpha; 3 layers: alpha/beta/alpha
198. Tombusvirus P19 core protein, VP19 [103144] (1)
     beta(2)-alpha-beta(2)-alpha; 2 layers: alpha/beta; antiparallel sheet: order 2134
199. Ribonuclease PH domain 2-like [55665] (1)
     beta(2)-alpha-beta(2)-alpha; 3 layers: alpha/beta/alpha; antiparallel sheet: order 2134
200. Regulatory factor Nef [55670] (1)
     alpha(2)-beta(4)-alpha; 3 layers: alpha/beta/alpha
201. CytB endotoxin-like [55675] (1)
     core: beta-alpha(2)-beta-alpha(2)-beta(4); 3 layers: a/b/a
202. Class II aaRS and biotin synthetases [55680] (1)
     contains large mixed beta-sheet
203. Subdomain of clathrin and coatomer appendage domain [55710] (1)
     beta-alpha-beta-alpha-beta(4)-alpha; 3 layers: a/b/a; bifurcated antiparallel beta-sheet
204. Sterol carrier protein, SCP [55717] (1)
     alpha-beta(3)-(crossover)-beta-(alpha)-beta; 3 layers: a/b/a; antiparallel beta-sheet of 5 strands; order: 32145
205. Ta1353-like [103164] (1)
     core: beta-alpha-beta(2)-alpha-beta-alpha-beta; 3 layers: a/b/a; antiparallel beta-sheet of 5 strands; order: 51423;
206. Mog1p/PsbP-like [55723] (1)
     (beta-hairpin)-beta(3)-alpha-beta(4)-alpha; 3 layers: a/b/a; antiparallel beta-sheet of 7 strands; order: 1237654
207. Acyl-CoA N-acyltransferases (Nat) [55728] (1)
     3 layers: a/b/a; contains mixed beta-sheet
208. Gelsolin-like [55752] (2)
     3 layers: a/b/a; contains mixed beta-sheet
209. PHP14-like [143723] (1)
     beta(3)-alpha-beta(2)-alpha-beta; 3 layers, a/b/a; mixed beta-sheet, half-barrel, order: 132456; strands 2 and 5 are antiparallel to the rest
210. Profilin-like [55769] (9)
     core: 2 alpha-helices and 5-stranded antiparallel sheet: order 21543; 3 layers: alpha/beta/alpha
211. Ligand-binding domain in the NO signalling and Golgi transport [111125] (1)
     an N-terminal helical bundle and the C-terminal alpha-beta(2)-alpha-beta(2) subdomain enclose a ligand-binding cavity
212. Phage tail protein-like [143748] (1)
     alpha-beta-X-beta(2)-alpha-beta(2); 2 layers: a/b; mixed beta-sheet: order 12354, strands 1 and 2 are parallel
213. PR-1-like [55796] (1)
     alpha-beta-alpha-beta-alpha(2)-beta(2); 3 layers, alpha/beta/alpha; mixed sheet: order 1342
214. Phoshotransferase/anion transport protein [55803] (1)
     beta-alpha(2)-beta(3)-alpha(3); 3 layers, alpha/beta/alpha; mixed sheet: order 1342; loop crossing
215. Nudix [55810] (1)
     beta(2)-alpha-beta(3)-alpha; 3 layers: alpha/beta/alpha; mixed sheet
     contains beta-grasp motif
216. 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain [55815] (1)
     core: alpha-beta(2)-alpha-beta(2)-alpha-beta; 3 layers; mixed sheet: order 31425
217. YrdC/RibB [55820] (1)
     core: alpha-beta(2)-alpha-beta-alpha(2)-beta(2)-alpha-beta-alpha-beta; 3 layers; mixed twisted sheet of 7 strands; order 7126354; strands 7 and 1 are parallel to each other
218. GIY-YIG endonuclease [82770] (1)
     beta(2)-alpha(2)-beta-alpha-(beta); strand 4 is very short; 3 layers; antiparallel (mixed) beta-sheet; order 312(4)
219. YbaK/ProRS associated domain [55825] (1)
     core: alpha-beta-alpha-beta(2)-(alpha-beta)2-alpha-beta(2)-alpha-beta; 3 layers; bifurcated mixed sheet
220. Thymidylate synthase/dCMP hydroxymethylase [55830] (1)
     contains large mixed beta-sheet
221. Thymidylate synthase-complementing protein Thy1 [69795] (1)
     complex alpha+beta fold; contains antiparallel 5-stranded beta-sheet: order 12354
222. N-acetylmuramoyl-L-alanine amidase-like [55845] (1)
     contains mixed beta-sheet
223. Cytochrome b5-like heme/steroid binding domain [55855] (1)
     beta-alpha-beta(2)-alpha(1,2)-(beta)-alpha(2)-beta; 3 layers: a/b/a; antiparallel beta-sheet, order: 1532(4)
224. DUSP-like [143790] (1)
     alpha-beta-alpha-X-beta-alpha-beta; three-helical bundle capped at one end by antiparallel beta-sheet, order: 213
225. DNA topoisomer