Structural Classification of Proteins
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Fold: CBS-domain

core: beta-alpha-beta(4); 2 layers: alpha/beta

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: CBS-domain [54630]
    core: beta-alpha-beta(4); 2 layers: alpha/beta

Superfamilies:

  1. CBS-domain [54631] (1)
    1. CBS-domain [54632] (13)
      Pfam 00571; pairs of CBS domains dimerize to form a stable globular domain
      1. Hypothetical protein TM0935 [102895]
        1. Thermotoga maritima [TaxId: 2336] [102896] (1) picpic
      2. Hypothetical protein MTH1622 [102897]
        1. Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262] [102898] (1) picpic
      3. Hypothetical protein Ta0289 [102899]
        contains extra C-terminal zinc-finger domain
        1. Archaeon Thermoplasma acidophilum [TaxId: 2303] [102900] (1) picpic
      4. Type II inosine monophosphate dehydrogenase CBS domains [54633]
        contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
        1. Human (Homo sapiens), type I [TaxId: 9606] [89899] (1) picpic
        2. Human (Homo sapiens), type II [TaxId: 9606] [54634] (3) picpic
        3. Chinese hamster (Cricetulus griseus) [TaxId: 10029] [64260] (1) picpic
        4. Streptococcus pyogenes [TaxId: 1314] [54635] (1) picpic
      5. Hypothetical protein YkuL [117881]
        1. Bacillus subtilis [TaxId: 1423] [117882] (1) picpic
      6. Nuclear protein SNF4 [143134]
        duplication: comprises four CBS repeats
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [143135] (1) picpic
      7. Hypothetical protein TM0892, CBS tandem [143136]
        1. Thermotoga maritima [TaxId: 2336] [143137] (4) picpic
      8. Chloride channel protein, CBS tandem [143138]
        contains additional structures between the two CBS repeats
        1. Marbled electric ray (Torpedo marmorata) [TaxId: 7788] [143139] (4) picpic
      9. Hypothetical protein VC0737 [143140]
        Putative acetoin utilization protein AcuB
        1. Vibrio cholerae [TaxId: 666] [143141] (4) picpic
      10. Hypothetical protein Rv2626c [143142]
        1. Mycobacterium tuberculosis [TaxId: 1773] [143143] (8) picpic

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MRC
site Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007
Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk