Protein: Type II inosine monophosphate dehydrogenase CBS domains from Human (Homo sapiens), type II [TaxId: 9606]

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: CBS-domain [54630]
   core: beta-alpha-beta(4); 2 layers: alpha/beta
4. Superfamily: CBS-domain [54631]
5. Family: CBS-domain [54632]
   Pfam 00571; pairs of CBS domains dimerize to form a stable globular domain
6. Protein: Type II inosine monophosphate dehydrogenase CBS domains [54633]
   contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
7. Species: Human (Homo sapiens), type II [TaxId: 9606] [54634]

PDB Entry Domains:

1. 1b3o
   complexed with cpr, sae
   1. region b:112-159 [38538]
   2. region b:178-231 [38539]
2. 1nf7
   both CBS domains are partly disordered in both chains, A and B
   complexed with k, myd, rvp
   1. region a:112-166 [91853]
   2. region a:170-231 [91854]
   3. region b:112-166 [91856]
   4. region b:170-231 [91857]
3. 1nfb
   both CBS domains are partly disordered in both chains, A and B
   complexed with cpr, nad
   1. region a:112-152 [91859]
   2. region a:188-231 [91860]
   3. region b:112-152 [91862]
   4. region b:188-231 [91863]

Generated from scop database 1.73 with scopm 1.101 on Wed Nov 21 11:18:32 2007 Copyright © 1994-2007 The scop authors / scop@mrc-lmb.cam.ac.uk