Structural Classification of Proteins

Superfamily: Complement control module/SCR domain

Lineage:

Root: scop
Class: Small proteins [56992]
Usually dominated by metal ligand, heme, and/or disulfide bridges
Fold: Complement control module/SCR domain [57534]
disulfide-rich all-beta fold
Superfamily: Complement control module/SCR domain [57535]

Families:

Complement control module/SCR domain [57536] (13)
Pfam 00084
1. Factor H, 15th and 16th modules [57537]
  1. Human (Homo sapiens) [TaxId: 9606] [57538] (3)
2. Complement control protein [57539]
  1. Vaccinia virus [TaxId: 10245] [57540] (15)
    a complement protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans
3. CD46 (membrane cofactor protein, MCP) [57541]
  1. Human (Homo sapiens) [TaxId: 9606] [57542] (5)
4. beta2-glycoprotein I [57543]
  consists of five modules with the C-terminal module fold being altered
  1. Human (Homo sapiens) [TaxId: 9606] [57544] (4)
5. Complement decay-accelerating factor (Daf, CD55) [90172]
  1. Human (Homo sapiens) [TaxId: 9606] [90173] (18)
6. Complement receptor 1, cr1 [75680]
  1. Human (Homo sapiens) [TaxId: 9606] [75681] (3)
7. Complement receptor 2, cr2 [64564]
  1. Human (Homo sapiens) [TaxId: 9606] [64565] (6)
8. Complement C1S protease domain [64566]
  1. Human (Homo sapiens) [TaxId: 9606] [64567] (1)
9. Complement C1R protease domains [75682]
  1. Human (Homo sapiens) [TaxId: 9606] [75683] (4)
10. Mannan-binding lectin serine protease 2 (MASP-2) domains [111409]
  1. Human (Homo sapiens) [TaxId: 9606] [111410] (2)
11. GABA-B receptor 1 [118257]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [118258] (2)
12. Complement factor B [144115]
  contains tandemrepeat of three SCR (Sushi) domains
  1. Human (Homo sapiens) [TaxId: 9606] [144116] (3)
13. Interleukin-2 receptor alpha chain [144117]
  consists of two segment-swapped SCR domains
  1. Human (Homo sapiens) [TaxId: 9606] [144118] (8)